Stable Istotope Labelled Olaratumab Biosimilar – Anti-PDGF-R alpha mAb – Research Grade

Reference: PX-TA1025-SIL-1MG
Product nameStable Istotope Labelled Olaratumab Biosimilar - Anti-PDGF-R alpha mAb - Research Grade
SourceDrugBank DB06043
SpeciesHuman
Expression systemMammalian cells
Molecular weight154kDa
Purity>95%
BufferPBS pH7.5
Delivery conditionBlue Ice
Delivery Time3-5 days if in stock; 5-8 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /SynonymsOlaratumab
ReferencePX-TA1025-SIL
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG1Kappa
ClonalityMonoclonal Antibody
SourceDrugBank DB06043
FormatLyophilized
LabellingArginine: 13C6,15N4 ; Lysine: 13C6,15N2, >99%
Isotopic Enrichment99%
Stability1 year
FormulaC6554H10076N1736O2048S40

General information about Olaratumab

Olaratumab is a fully human IgG1 monoclonal antibody with antitumor activity that selectively binds the external domain of human platelet-derived growth factor receptor (PDGFR)-? with high affinity and blocks ligand binding. It is composed of two heavy chain molecule fragments and 2 light chain fragments. Studies show that the treatment of olaratumab in combination with doxorubicin resulted in significant reduction of cancer cell proliferation and tumor growth. This product is for research use only.

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