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RECOMBINANT ANTIBODY SERVICE

Need to screen or characterize an antibody? Get 1 mg of recombinant antibody in 4 weeks to use in antibody screening, characterization, preclinical studies, and any other small-scale applications. Our proprietary mammalian expression system – XtenCHO™ – is the market’s leader… Read More

FAQs – Recombinant antibodies

Recombinant antibodies are one of the most successful biological reagents for research, therapy, and diagnostics. Their use has become widespread due to the enhanced batch-to-batch consistency and purity obtained by recombinant antibody production methods. On this page, we answer all most frequently asked… Read More

How are recombinant antibodies produced?

Recombinant antibodies are monoclonal antibodies produced in recombinant expression systems. Their production process starts by taking the antibody-encoding genes from different sources and transfecting them into highly productive systems, while the term monoclonal antibody is more commonly used to describe antibodies natively produced by hybridomas. Check out other… Read More

What is a recombinant antibody?

Recombinant antibodies can be defined by comparison with conventional monoclonal antibodies. In this article, we cover the essential definition of recombinant antibodies and explain why these reagents are quickly replacing conventional monoclonal antibodies from hybridomas in many applications. Check out other frequently asked questions (FAQs) about recombinant… Read More

What are the benefits of using recombinant antibodies?

Recombinant antibodies are useful for many applications. Unlike conventional monoclonal antibodies produced in hybridomas, recombinant antibodies can be produced in different high-yield expression systems. But although diagnostic and therapeutic antibodies are generally produced in recombinant systems, most research antibodies are still produced in hybridomas. However, there are many… Read More

FAQs – Stable cell lines for monoclonal antibody production

How can we help? Got a question about our phage display platform or need a quote? Message us and we’ll get back to you in 48 hours or less. Contact Us… Read More

What are the benefits of generating stable cell lines for monoclonal antibody production?

Stable cell line generation for monoclonal antibody production is one of the most crucial steps to ensure the commercial viability of new biotherapeutics and diagnostic tools. Despite being an expensive, time and labor-intensive process, stable expression is currently the only suitable method for the production of large quantities… Read More

What is the difference between transient and stable monoclonal antibody production?

Monoclonal antibodies can be produced in mammalian systems using either transient or stable expression approaches. These two approaches have well-known advantages and limitations and each remains useful for different purposes and applications. In this article, we discuss the main differences between transient and stable monoclonal antibody production and… Read More

What are the main cell lines used for the stable production of monoclonal antibodies?

The stable production of antibodies, particularly therapeutic monoclonal antibodies, has long been dominated by mammalian recombinant systems. Despite their complex genetic background, cell lines like Chinese hamster ovary (CHO) and murine myeloma cells, are very amenable to growth in suspension in serum-free medium and highly tolerant to changes… Read More

How long does it take to generate stable cell lines for monoclonal antibody production?

The process of stable cell line generation is a laborious process reserved for the large-scale production of monoclonal antibody pharmaceuticals. In this article, we explain our recommendations and approaches to monoclonal antibody production. We detail the average lead times for this process. Check out other frequently asked… Read More