Stable Istotope Labelled Natalizumab Biosimilar – Anti-ITGA4/CD49d mAb – Research Grade

Reference: PX-TA1053-SIL-1MG
Product nameStable Istotope Labelled Natalizumab Biosimilar - Anti-ITGA4/CD49d mAb - Research Grade
SourceCAS 189261-10-7
SpeciesHumanized
Expression systemMammalian cells
Purity>95%
BufferPBS buffer PH7.5
Delivery conditionBlue Ice
Delivery Time3-5 days if in stock; 5-8 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
Aliases /SynonymsAN 100226,BG00002
ReferencePX-TA1053-SIL
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG4-kappa
ClonalityMonoclonal Antibody
SourceCAS 189261-10-7
FormatLyophilized
LabellingArginine: 13C6,15N4 ; Lysine: 13C6,15N2, >99%
Isotopic Enrichment99%
Stability1 year

General information on Anti-ITGA4/CD49d(Homo sapiens) (Natalizumab) Monoclonal Antibody

Natalizumab is a humanized monoclonal antibody produced in murine myeloma cells of isotype IgG4k. Natalizumab contains a human framework region and a complementarity determining region of a murine antibody that binds to ?4-integrin. Natalizumab has been temporarily discontinued due to the risk of progressive multifocal leukoencephalopathy (PML).

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