Ranibizumab Biosimilar – Anti-VEGF mAb – Research Grade

Reference:
Product nameRanibizumab Biosimilar - Anti-VEGF mAb - Research Grade
SourceDrugBank DB01270
SpeciesHuman
Expression systemMammalian cells
Molecular weight48kDa
Purity>85%
BufferPBS pH7.5
Delivery conditionBlue ice (+4°C)
Delivery Time3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
ApplicationsELISA,WB
Aliases /SynonymsRanibizumab,Ranibizumab,VEGF,anti-VEGF
ReferencePX-TA1008
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeFabG1
ClonalityMonoclonal Antibody

Description of Ranibizumab Biosimilar - Anti-VEGF mAb - Research Grade

General information about Ranibizumab

Ranibizumab is a monoclonal antibody fragment (Fab) created from the same parent mouse antibody as bevacizumab. It is an anti-angiogenic that has been approved to treat the “wet” type of age-related macular degeneration (AMD, also ARMD), diabetic retinopathy, and macular edema due to branch retinal vein occlusion or central retinal vein occlusion. This product is for research use only.

SDS-PAGE for Ranibizumab Biosimilar - Anti-VEGF mAb

Ranibizumab Biosimilar - Anti-VEGF mAb, on SDS-PAGE under non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.

Ranibizumab Biosimilar - Anti-VEGF mAb binds to VEGFA / VEGF165, C-His, recombinant protein in Indirect ELISA

Immobilized VEGFA / VEGF165, C-His, recombinant protein (cat. No. PX-P5977) at 0.5µg/mL (100µL/well) can bind Ranibizumab Biosimilar - Anti-VEGF mAb (cat. No. PX-TA1008) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450 giving an EC50 at 22.11M.

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