Stable Istotope Labelled Ramucirumab Biosimilar – Anti-VEGFR-2 mAb – Research Grade

Reference: PX-TA1023-SIL-1MG
Product nameStable Istotope Labelled Ramucirumab Biosimilar - Anti-VEGFR-2 mAb - Research Grade
SourceDrugBank DB05578
SpeciesHuman
Expression systemMammalian cells
Molecular weight143kDa
Purity>95%
BufferPBS pH7.5
Delivery conditionBlue Ice
Delivery Time3-5 days if in stock; 5-8 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /SynonymsRamucirumab
ReferencePX-TA1023-SIL
Related ProductsPX-P3059
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG1Kappa
ClonalityMonoclonal Antibody
SourceDrugBank DB05578
FormatLyophilized
LabellingArginine: 13C6,15N4 ; Lysine: 13C6,15N2, >99%
Isotopic Enrichment99%
Stability1 year
FormulaC6374H9864N1692O1996S46

General information about Ramucirumab

Ramucirumab is a monoclonal antibody. Monoclonal antibodies are created in a lab to attach to the targets found on specific types of cancer cells. The antibody “calls” the immune system to attack the cell it is attached to, resulting in the immune system killing the cell. These antibodies can work in different ways, including stimulating the immune system to kill the cell, blocking cell growth or other functions necessary for cell growth. Ramucirumab inhibits the activity of vascular endothelial growth factor (VEGF). VEGF is responsible for angiogenesis, or the development of new blood vessels by and for the tumor (or any tissue), so blocking VEGF’s activity prevents the growth of new blood vessels, essentially cutting off the tumor’s source of nutrients. This product is for research use only.

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