Stable Isotope Labelled Ocrelizumab Biosimilar – Anti-MS4A1/CD20 mAb – Research Grade

Reference: PX-TA1162-SIL-1MG
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Expression system

Applications

Product nameStable Isotope Labelled Ocrelizumab Biosimilar - Anti-MS4A1/CD20 mAb - Research Grade
SourceCAS 637334-45-3
SpeciesHumanized
Expression systemMammalian cells
Molecular weight145kDa
Purity>95%
BufferPBS buffer PH7.5
Delivery conditionBlue Ice
Delivery Time3-5 days if in stock; 5-8 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
ApplicationsMS
Aliases /Synonyms2H7
ReferencePX-TA1162-SIL
Related ProductsPX-P3060
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG1-nd
ClonalityMonoclonal Antibody
FormatLyophilized
LabellingArginine: 13C6,15N4 ; Lysine: 13C6,15N2, >99%
Isotopic Enrichment99%
Stability1 year

General information on Anti-MS4A1/CD20(Homo sapiens) (Ocrelizumab) Monoclonal Antibody

Ocrelizumab is a CD20-directed cytolytic antibody, which is suitable for the treatment of patients with relapsed or primary progressive multiple sclerosis. It is a second-generation recombinant humanized monoclonal antibody of isotype IgG1 that can selectively target B lymphocytes expressing CD20 antigen. Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system, which can cause neurological dysfunction. Most patients with MS experience recurrent episodes with functional deterioration, followed by recovery or remission.

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