Stable Istotope Labelled Golimumab Biosimilar – Anti-TNFA/TNF alpha mAb – Research Grade
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| Product name | Stable Istotope Labelled Golimumab Biosimilar - Anti-TNFA/TNF alpha mAb - Research Grade |
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| Source | CAS 476181-74-5 |
| Species | Homo sapiens |
| Expression system | Mammalian cells |
| Molecular weight | 147kDa |
| Purity | >95% |
| Buffer | PBS buffer PH7.5 |
| Delivery condition | Blue Ice |
| Delivery Time | 3-5 days if in stock; 5-8 weeks if production needed |
| Storage condition | store at -80°C |
| Brand | ProteoGenix |
| Aliases /Synonyms | CNTO 148 |
| Reference | PX-TA1129-SIL |
| Related Products | PX-P3058 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype | IgG1-kappa |
| Clonality | Monoclonal Antibody |
| Format | Lyophilized |
| Labelling | Arginine: 13C6,15N4 ; Lysine: 13C6,15N2, >99% |
| Isotopic Enrichment | 99% |
| Stability | 1 year |
General information on Anti-TNFA/TNF alpha(Homo sapiens) (Golimumab) Monoclonal Antibody
Golimumab is a human IgG1? monoclonal antibody, developped from genetically engineered mice immunized with human TNF?. Golimumab binds to and inhibits soluble and transmembrane human TNF?. Elevated TNF? is related to chronic inflammation. Therefore, golimumab can be used in adults,for the treatment of active rheumatoid arthritis (RA), active psoriatic arthritis ( PsA), active ankylosing spondylitis (AS), ulcerative colitis (UC). In the United States and Canada, golimumab is sold under the Simponi® brand. The FDA label includes a black box that warns of serious infections and malignant tumors.
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