Stable Istotope Labelled Denosumab Biosimilar – Anti-RANKL mAb – Research Grade

Reference: PX-TA1018-SIL-1MG
Product nameStable Istotope Labelled Denosumab Biosimilar - Anti-RANKL mAb - Research Grade
SourceDrugBank DB06643
SpeciesHuman
Expression systemMammalian cells
Molecular weight144kDa
Purity>95%
BufferPBS pH7.5
Delivery conditionBlue Ice
Delivery Time3-5 days if in stock; 5-8 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /SynonymsDenosumab
ReferencePX-TA1018-SIL
Related ProductsPX-P4774
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG2Kappa
ClonalityMonoclonal Antibody
SourceDrugBank DB06643
FormatLyophilized
LabellingArginine: 13C6,15N4 ; Lysine: 13C6,15N2, >99%
Isotopic Enrichment99%
Stability1 year
FormulaC6404H9912N1724O2004S50

General information about Denosumab

Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption markers in patients with a variety of metastatic tumors and is being investigated in multiple clinical trials for the prevention and treatment of bone metastases. Chemically, it consists of 2 heavy and 2 light chains. Each light chain consists of 215 amino acids. Each heavy chain consists of 448 amino acids with 4 intramolecular disulfides.This product is for research use only.

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