Stable Istotope Labelled Reslizumab Biosimilar – Anti-IL5 mAb – Research Grade
|Product name||Stable Istotope Labelled Reslizumab Biosimilar - Anti-IL5 mAb - Research Grade|
|Expression system||Mammalian cells|
|Buffer||PBS buffer PH7.5|
|Delivery condition||Blue Ice|
|Delivery Time||3-5 days if in stock; 5-8 weeks if production needed|
|Storage condition||store at -80°C|
|Note||For research use only. Not suitable for clinical or therapeutic use.|
|Labelling||Arginine: 13C6,15N4 ; Lysine: 13C6,15N2, >99%|
General information on Anti-IL5(Homo sapiens) (Reslizumab) Monoclonal Antibody
Reslizumab is a humanized interleukin 5 (IL-5) antagonist monoclonal antibody (IgG4 kappa), produced by recombinant DNA technology in murine non-secretory myeloma 0 (NS0) cells. IL-5 is a pro-inflammatory cytokine responsible for the growth and differentiation, recruitment, activation and survival of eosinophil markers. Elevated levels of eosinophils increase the risk of exacerbation of asthma, including allergic and non-allergic forms of asthma characterized by eosinophilia. By targeting IL-5 and disrupting its signaling pathway, reslizumab aims to inhibit the maturation of eosinophils and promote programmed cell death. Reslizumab is sold as Cinqaero in Europe.
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