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100ug
ProteoGenix
Recombinant Proteins
Mammalian cells
Elisa, WB
CD53 is a member of the transmembrane superfamily 4, also known as the tetraspanin family. Most of these members are cell surface proteins, which are characterized by the presence of four hydrophobic domains. These proteins measure signal transduction events that play a role in regulating cell development, activation, growth and movement. CD53 is a cell surface glycoprotein known to be complex with integrins. Common defects in the CD53 gene are linked to immunodeficiency, which is related to recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of signals produced by CD2 in T cells and natural lethal cells and is thought to play a role in regulating growth.
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