CD317 Recombinant Protein

Reference: PX-P4118-100



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Origin Species

Description of CD317 Recombinant Protein

General Information about CD317 Recombinant Protein

Tetherin, also known as bone marrow antigen 2, is a lip-associated protein and is encoded by the BST2 gene in humans. Furthermore, Tetherin was named CD317 (differentiated aggregate 317). The protein is structurally expressed in mature B cells, plasma cells, and plasma dendritic cells. In many other cells, it is expressed only in response to stimulation of the IFN pathway.
Tetherin is a human cell protein that prevents retroviral infection by preventing the spread of virus particles after budding from infected cells. Tetherin was originally found to act as an inhibitor of HIV-1 infection without lack of Vpu, but it has also been shown to inhibit the release of other RNA viruses (such as Lassa and Marburg virgin), indicating a form of prevent the release of encapsulated viruses without interacting with males. The common mechanism of protein interaction. Furthermore, Tetherin also limits the neural invasion of the HSV-1 DNA virus.

Product nameCD317 Recombinant Protein
Origin speciesHomo sapiens (Human)
Expression systemProcaryotic expression
Molecular weight39.49kDa
Purity estimated>90% by SDS-PAGE
BufferN-terminal Gst Tag
Delivery conditionDry Ice
Storage conditionStore at - 20? to -80?. It is recommended that the protein be aliquoted for optimal storage.
Host speciesEscherichia coli (E.coli)
Fragment TypeSer50~Ser161
Aliases /Synonyms/
NoteFor research use only


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