CD132 Recombinant Protein
Size | 100ug |
---|---|
Brand | |
Product type | |
Host Species |
Description of CD132 Recombinant Protein
General information on CD132 Recombinant Protein:
The common gamma chain (?c) (or CD132), also known as the interleukin 2 receptor ? or IL2RG subunit, is a member of the type I cytokine family and is expressed in most lymphocytes (leukocytes) and its cells in mammals. A gene was found on its X chromosome. The common ? (?c) chain (or IL2RG) is the cytokine receptor subunit, which is the cytokine receptor subunit shared by the receptor complexes of at least six different interleukin receptors. IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin 21 receptors. It is a component of many cytokine receptors, which are essential for the development and function of lymphocytes. Severe X-linked combined immunodeficiency (XSCID) is a rare and life-threatening disease caused by mutations in IL2RG (the gene that encodes IL2RG). Based on chemical binding data, IL2RG has been shown to be a component of the IL-4 receptor, that is, the ability of IL2RG to increase IL-4 binding affinity. The observation that the IL-2R range is a functional part of the IL-4 receptor, and the discovery that IL-2R? is related to the IL-7 receptor, began to explain why the lack of this ? chain common (?c) has an impact on lymphatic development and function. It has a profound impact, as seen in X-linked severe combined immunodeficiency.
Product name | CD132 Recombinant Protein |
---|---|
Origin species | Homo sapiens (Human) |
Expression system | Eukaryotic expression |
Molecular weight | 30.70kDa |
Purity estimated | >90% by SDS-PAGE |
Buffer | C-terminal His Tag |
Delivery condition | Dry Ice |
Storage condition | Store at - 20? to -80?. It is recommended that the protein be aliquoted for optimal storage. |
Brand | ProteoGenix |
Host species | Mammalian cells |
Fragment Type | Met1-Asn254 |
Aliases /Synonyms | IL2RG |
Reference | PX-P4105 |
Note | For research use only |
Reviews
There are no reviews yet.