DNA topoisomerase 3-alpha (TOP3A)

Reference: PX-P4289-100



Product type

Host Species

Description of DNA topoisomerase 3-alpha (TOP3A)

General information on DNA topoisomerase 3-alpha (TOP3A):

DNA topoisomerase 3-alpha is an enzyme encoded by the TOP3A gene in humans. This gene encodes DNA topoisomerase, an enzyme that controls and changes the topological state of DNA during transcription. This enzyme catalyzes the instantaneous breaking and agglomeration of single strands of DNA, which allows strands to cross each other, thereby reducing the number of supershells and altering the topological structure of DNA. The enzyme forms a complex with BLM, which can regulate the reorganization of somatic cells.

Product nameDNA topoisomerase 3-alpha (TOP3A)
Expression systemEukaryotic expression
Molecular weight35.29kDa
Purity estimated>90% by SDS-PAGE
Buffer50mM Tris-Cl pH 8.0, 150mM NaCl.
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Host speciesInsect
Fragment TypeGlu631-Phe926
Aliases /Synonyms/
NoteFor research use only


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