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Brand: ProteoGenix

DNA topoisomerase 3-alpha (TOP3A)

Host species:
Insect
Uniprot ID:
Q9LVP1
Molecular weight:
35.29kDa

420.00

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Glu631–Phe926
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DNA topoisomerase 3-alpha (TOP3A)

Product name DNA topoisomerase 3-alpha (TOP3A)
Uniprot ID Q9LVP1
Uniprot link https://www.uniprot.org/uniprot/Q9LVP1
Expression system Eukaryotic expression
Sequence MGASWSHPQFEKGGGSGGGSGGSAWSHPQFEKLEVLFQGESQTAGEVVRRCNLCNESDMALRKNRDGNFMVGCMNYPQCRNAVWLPGPTLEASVTTNVCQSCGPGPVYKILFKFRQIGIPPGFDVNHLGCVGGCDDILKQLIDICGTGSRSQARRTPGTAPSNNIQGSNTRQSNVCIHCQQRGHASTNCPSRVPASRNSRPTATNPRNDESTVSCNTCGSQCVLRTANTEANRGRQFFSCPTQGCSFFAWEDSINNSSGNATTGSNSGGSGRRGSRGRGRGGRGGQSSGGRRGSGTSFVSATGEPVSGIRCFSCGDPSHFANACPNRNNSNGNYF
Molecular weight 35.29kDa
Purity estimated >90% by SDS-PAGE
Buffer 50mM Tris-Cl pH 8.0, 150mM NaCl.
Delivery condition Dry Ice
Delivery lead time in business days Europe: 5-7 working days
USA & Canada: 7-10 working days
Rest of the world: 5-12 working days
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Insect
Fragment Type Glu631-Phe926
Aliases /Synonyms /
Reference PX-P4289
Note For research use only
Background information Array
Molecular Constructor
Glu631–Phe926

General information on DNA topoisomerase 3-alpha (TOP3A):

DNA topoisomerase 3-alpha is an enzyme encoded by the TOP3A gene in humans. This gene encodes DNA topoisomerase, an enzyme that controls and changes the topological state of DNA during transcription. This enzyme catalyzes the instantaneous breaking and agglomeration of single strands of DNA, which allows strands to cross each other, thereby reducing the number of supershells and altering the topological structure of DNA. The enzyme forms a complex with BLM, which can regulate the reorganization of somatic cells.

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