CD272 Recombinant Protein

Reference: PX-P4114-100



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Origin Species

Description of CD272 Recombinant Protein

General Information about CD272 Recombinant Protein

CD272 (cluster of differentiation 272) is also designated as BTLA. BTLA expression is induced during T cell activation and BTLA is still expressed on Th1 cells instead of Th2 cells. Like PD1 and CTLA4, BTLA interacts with homologs B7 and B7H4. However, unlike PD-1 and CTLA-4, BTLA exhibits an inhibitory effect on T lymphocytes by interacting with familial neurotic tumor receptors (TNF-R), not just with cell surface receptors. Family interaction. BTLA is a linker of tumor necrosis factor 14 superfamily member (receptor) (TNFRSF14) and is also known as herpes virus mediator (HVEM). The BTLA-HVEM complex negatively regulates the immune response of T cells. Activation of BTLA inhibits the function of cancer-specific human CD8 + T cells.

Product nameCD272 Recombinant Protein
Origin speciesHomo sapiens (Human)
Expression systemEukaryotic expression
Molecular weight32kDa
Purity estimated>90% by SDS-PAGE
BufferC-terminal His Tag
Delivery conditionDry Ice
Storage conditionStore at - 20? to -80?. It is recommended that the protein be aliquoted for optimal storage.
Host speciesMammalian cells
Fragment TypeMet1~Ser150
Aliases /Synonyms/
NoteFor research use only


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