CD272 Recombinant Protein

Reference: PX-P4114-100
Size

100ug

Brand

Product type

Host Species

Origin Species

Description of CD272 Recombinant Protein

General Information about CD272 Recombinant Protein

CD272 (cluster of differentiation 272) is also designated as BTLA. BTLA expression is induced during T cell activation and BTLA is still expressed on Th1 cells instead of Th2 cells. Like PD1 and CTLA4, BTLA interacts with homologs B7 and B7H4. However, unlike PD-1 and CTLA-4, BTLA exhibits an inhibitory effect on T lymphocytes by interacting with familial neurotic tumor receptors (TNF-R), not just with cell surface receptors. Family interaction. BTLA is a linker of tumor necrosis factor 14 superfamily member (receptor) (TNFRSF14) and is also known as herpes virus mediator (HVEM). The BTLA-HVEM complex negatively regulates the immune response of T cells. Activation of BTLA inhibits the function of cancer-specific human CD8 + T cells.

Product nameCD272 Recombinant Protein
Origin speciesHomo sapiens (Human)
Expression systemEukaryotic expression
Molecular weight32kDa
Purity estimated>90% by SDS-PAGE
BufferC-terminal His Tag
Delivery conditionDry Ice
Storage conditionStore at - 20? to -80?. It is recommended that the protein be aliquoted for optimal storage.
BrandProteoGenix
Host speciesMammalian cells
Fragment TypeMet1~Ser150
Aliases /Synonyms/
ReferencePX-P4114
NoteFor research use only

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