General information on CD226 Recombinant Protein:
The cluster of differentiation system (CD) is commonly used as a cell marker for immunophenotyping. Different types of cells in the immune system can be identified by surface CD molecules related to cellular immune function. More than 32 unique CD groups and subcategories have been identified. Some CD molecules act as important receptors or ligands for cells, starting a signal cascade and then altering the cell’s behavior. Some CD proteins are not involved in the cell signaling process, but have other functions, such as cell incorporation. CD226, also known as PTA1 or DNAM-1, is a member of the immunoglobulin superfamily, which contains two Ig-like domains from group V. A high rate of CD226 (differentiation cluster 226) has been found on the surface of natural lethal cells, platelets, monocytes and some T cells. CD226 has binding sites for CD112 and CD155 and mediates cell adhesion to other cells containing their ligands.
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