CD122 Recombinant Protein
Size | 100ug |
---|---|
Brand | |
Product type | |
Host Species | |
Origin Species |
Description of CD122 Recombinant Protein
General information on CD122 Recombinant Protein:
The interleukin-2 receptor (IL-2R), also known as the ? subunit receptor of the ? subunit IL-2, subunit of the IL-2 ? and IL-2RB receptor, participates in the immune response of T cells. ability to bind interleukin 2, CD122 / IL-2RB exists in three forms. The low affinity form is a monomer of the alpha subunit and does not participate in signal transmission. The intermediate affine form is composed of ? / ? subunit heterodimers, while the high affinity form is composed of ? / ? / gamma heterotrimers. Both forms of medium and high affinity for CD122 / IL-2RB are involved in receptor-mediated endocytosis and interleukin-2-mediated mitotic signal transduction. CD122 / IL-2RB expression is limited to older B22 + cells (CD43 + CD24- prepro B cells, fraction A), which can proliferate to IL-2 strongly without any stromal cells, but not to IL-15 A High affinity form of the receptor is expressed in activated T lymphocytes, activated B lymphocytes and activated macrophages. CD122 / IL-2RB plays a role in regulating normal lymphocyte development.
Product name | CD122 Recombinant Protein |
---|---|
Origin species | Homo sapiens (Human) |
Expression system | Eukaryotic expression |
Molecular weight | 35-45kDa |
Purity estimated | >90% by SDS-PAGE |
Buffer | C-terminal His Tag |
Delivery condition | Dry Ice |
Storage condition | Store at - 20? to -80?. It is recommended that the protein be aliquoted for optimal storage. |
Brand | ProteoGenix |
Host species | Mammalian cells |
Fragment Type | Met1-Asp239 |
Aliases /Synonyms | IL2RB |
Reference | PX-P4103 |
Note | For research use only |
Reviews
There are no reviews yet.