CD102 Recombinant Protein

Reference: PX-P4097-100
Product nameCD102 Recombinant Protein
Uniprot IDP13598
Uniprot link
Origin speciesHomo sapiens (Human)
Expression systemEukaryotic expression
Molecular weight45kDa
Protein delivered with Tag?C-terminal His Tag
Purity estimated>90% by SDS-PAGE
BufferPBS pH7.5
Delivery conditionDry Ice
Storage conditionStore at - 20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage.
Host speciesMammalian cells
Fragment TypeMet1~Gln223
Aliases /Synonyms/
NoteFor research use only

Description of CD102 Recombinant Protein

General information on CD102 Recombinant Protein:

The intercellular adhesion molecule 2 (ICAM-2, CD102) belongs to the ICAM family and consists of three members, which are identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-like domains and binds to the leukocyte integrins LFA-1 (CD11a / CD18) and Mac-1 (CD11b / CD18). As the second ligand of antigen 1 associated with leukocyte function, ICAM-2 acts as an effective cell costimulatory molecule. ICAM-2 is expressed primarily in vascular endothelial cells and hematopoietic cells. The interaction of ICAM-2 and the integrin receptor mediates cell adhesion of a wide range of lymphocytes, monocytes, natural lethal cells, and granulocytes to other cells, and plays an important role in many immune and inflammatory responses. For example, T lymphocyte aggregation, NK cytotoxic lymphocyte migration, lymphocyte recirculation, etc. ICAM-2 series levels are significantly related to inflammation and trichinosis disease sequence in mice, and have a similar relationship to blood eosinophilia. Therefore, assessing serum ICAM-2 levels can help diagnose a recent trichinosis infection and monitor prognosis and response to treatment.


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