CD102 Recombinant Protein
Size | 100ug |
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Brand | |
Product type | |
Host Species |
Description of CD102 Recombinant Protein
General information on CD102 Recombinant Protein:
The intercellular adhesion molecule 2 (ICAM-2, CD102) belongs to the ICAM family and consists of three members, which are identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-like domains and binds to the leukocyte integrins LFA-1 (CD11a / CD18) and Mac-1 (CD11b / CD18). As the second ligand of antigen 1 associated with leukocyte function, ICAM-2 acts as an effective cell costimulatory molecule. ICAM-2 is expressed primarily in vascular endothelial cells and hematopoietic cells. The interaction of ICAM-2 and the integrin receptor mediates cell adhesion of a wide range of lymphocytes, monocytes, natural lethal cells, and granulocytes to other cells, and plays an important role in many immune and inflammatory responses. For example, T lymphocyte aggregation, NK cytotoxic lymphocyte migration, lymphocyte recirculation, etc. ICAM-2 series levels are significantly related to inflammation and trichinosis disease sequence in mice, and have a similar relationship to blood eosinophilia. Therefore, assessing serum ICAM-2 levels can help diagnose a recent trichinosis infection and monitor prognosis and response to treatment.
Product name | CD102 Recombinant Protein |
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Origin species | Homo sapiens (Human) |
Expression system | Eukaryotic expression |
Molecular weight | 45kDa |
Purity estimated | >90% by SDS-PAGE |
Buffer | C-terminal His Tag |
Delivery condition | Dry Ice |
Storage condition | Store at - 20? to -80?. It is recommended that the protein be aliquoted for optimal storage. |
Brand | ProteoGenix |
Host species | Mammalian cells |
Fragment Type | Met1~Gln223 |
Aliases /Synonyms | / |
Reference | PX-P4097 |
Note | For research use only |
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