Adalimumab Biosimilar – Anti-TNF alpha mAb – Research Grade

Validated

In: ELISA

(1 customer review)
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Description of Adalimumab Biosimilar - Anti-TNF alpha mAb - Research Grade

General information about Adalimumab

Adalimumab is a recombinant, human IgG1 monoclonal antibody directed against tumor necrosis factor-alpha (TNF-alpha), with immunomodulating activity. Upon administration, adalimumab binds to TNF-alpha, thereby preventing its binding to the p55 and p75 TNF cell surface receptors and inhibiting TNF-mediated immune responses. TNF-alpha, a pro-inflammatory cytokine, is upregulated in various autoimmune diseases. Check for active clinical trials using this agent.

Product nameAdalimumab Biosimilar - Anti-TNF alpha mAb - Research Grade
SourceDrugBank DB00051
SpeciesHuman
Expression systemMammalian cells
Molecular weight144kDa
Purity>90%
BufferPBS pH7.5
Delivery conditionDry Ice
Delivery Time3-5 days if in stock; 3-5 weeks if production needed
Storage condition4°C for short term; -20°C for long term
BrandProteoGenix
Aliases /SynonymsAdalimumab
ReferencePX-TA1001
Related ProductsTumor necrosis factor(TNF)
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG1
ClonalityMonoclonal Antibody
SourceDrugBank DB00051

1 review for Adalimumab Biosimilar – Anti-TNF alpha mAb – Research Grade

  1. Ofer Gover

    In which application did you use the antibody?: ELISA

    Did it work in your application?: Yes

    We used this ab to reduce as a negative control for reducing caco-2 (IEC) cells exitation by exugenues TNFa. We measured IL8 secreation as a result of TNFa stimulation. 1ug/mL ofAdalimumab Biosimilar – Anti-TNF alpha mAb was enough to completly abolish IL8 secreation by TNFa stimulation in caco-2 cells.

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