MousePAD2 Protein-arginine deiminase type-2 Mouse Recombinant Protein

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Description of MousePAD2 Protein-arginine deiminase type-2 Mouse Recombinant Protein

Description of MousePAD2 Protein-arginine deiminase type-2 Mouse Recombinant Protein

General Information about Mouse PAD2 (PADI2)

Mouse PAD2 (PADI2) is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions.

PADI2 has peptidylarginine deiminase activity against synthetic substrates. PAD2 is mainly expressed in the central nervous system, skeletal muscle, spinal cord, cerebrum, cerebellum, and submaxillary gland. Protein arginine deiminase type-2 plays a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis.

Eukaryote expression systems and more specifically Insect cells are used at ProteoGenix to produce mouse PAD2 recombinant protein with appropriate post translational modifications.

Product nameMousePAD2 Protein-arginine deiminase type-2 Mouse Recombinant Protein
Origin speciesHouse Mouse
Expression systemEukaryotic expression
Molecular weight79.36 kDa
Purity estimated95%
Buffer50mM Tris-Cl pH 8.0, 150mM NaCl
FormLyophilized
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesInsect
Fragment TypeFull-length
Aliases /SynonymsPAD-H19, PAD2, PDI2, Peptidylarginine deiminase II
ReferencePX-P3022
Publications1. F. Arnoux and al (2017).
Peptidyl arginine deiminase immunization induces anticitrullinated protein antibodies in mice with particular MHC types.
NoteFor research use only
Product nameMousePAD2 Protein-arginine deiminase type-2 Mouse Recombinant Protein
Origin speciesHouse Mouse
Expression systemEukaryotic expression
Molecular weight79.36 kDa
Purity estimated95%
Buffer50mM Tris-Cl pH 8.0, 150mM NaCl
FormLyophilized
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesInsect
Fragment TypeFull-length
Aliases /SynonymsPAD-H19, PAD2, PDI2, Peptidylarginine deiminase II
ReferencePX-P3022
Publications1. F. Arnoux and al (2017).
Peptidyl arginine deiminase immunization induces anticitrullinated protein antibodies in mice with particular MHC types.
NoteFor research use only

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