CAR-T cell therapy

  • The structure of CAR-T cells

    The structure of CAR-T cells

    Ana Reis, PhD Ana Reis, PhD 7 min read

    CAR-T cell therapy is an emerging alternative to conventional anticancer treatments. Over the years, these modified cells have demonstrated promising therapeutic efficacy spurning research in this field. Despite their complexity…

  • CAR-T cell immunotherapy
    CAR-T cell therapy

    CAR-T cell immunotherapy

    CAR-T cells are a form of adoptive T cell therapy (ACT). This emerging technology combines the cytotoxic potential of T… Read More

  • CAR-T cell engineering: strategies to overcome remaining limitations
    CAR-T cell therapy

    CAR-T cell engineering: strategies to overcome remaining limitations

    CAR-T cell engineering is an active field of research. Due to the complexity of these biotherapies, a multi-faceted approach must… Read More

  • How to manufacture CAR-T cells
    CAR-T cell therapy

    How to manufacture CAR-T cells

    Manufacturing CAR-T cells is a complex process requiring the collection of T cells from autologous or allogeneic sources and subsequent… Read More

  • From the first to the fifth generation of CAR-T cells
    CAR-T cell therapy

    From the first to the fifth generation of CAR-T cells

    Prompted by encouraging clinical and preclinical results, the structure of CAR-T cells has evolved rapidly to minimize off-target toxicity and… Read More