Zika virus NS1 Recombinant Protein

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Description of Zika virus NS1 Recombinant Protein

Description of Zika virus NS1 Recombinant Protein

Description of Zika virus NS1 Recombinant Protein

Description of Zika virus NS1 Recombinant Protein

General information on Zika virus NS1 Recombinant Protein

Zika Virus non-structural protein 1 (ZIKV NS1) is an approximately 48 kDa viral glycoprotein (1). Zika Virus is a mosquito-borne flavivirus and has been implicated an association with neonatal microcephaly and neurological disorders such as Guillain-Barré syndrome (2). ZIKV strain MR 766 was isolated from monkey host. ZIKV NS1 is a multifunctional virulence factor. The glycosylated NS1 exists as a membrane-associated dimer after translocation into the endoplasmic reticulum lumen, where it is essential for viral genome replication (1, 2). Infected cells secrete NS1 as a lipoprotein, which is involved in immune evasion and pathogenesis via interaction with components of the innate and adaptive immune systems (1, 2). Mature ZIKV NS1 contains 352 amino acids (aa) and has a hexameric conformation consisting of three dimers to form a symmetric barrel shape (1). It has high structural similarity to other flavivirus NS1 proteins, such as DENV and WNV (2, 3). Mature NS1 of ZIKV strain MR 766 shares 98% aa sequence identity with NS1 of ZIKV strain H/PF/2013 that was isolated from human host.

Product nameZika virus NS1 Recombinant Protein
Origin speciesZika virus
Expression systemProcaryotic expression
Molecular weight42.3 kDa
Purity estimated80%
BufferPBS,pH 7.5
FormFrozen
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesEscherichia coli (E.coli)
Fragment TypePartial
Aliases /SynonymsNS1
ReferencePX-P3025
NoteFor research use only
Product nameZika virus NS1 Recombinant Protein
Origin speciesZika virus
Expression systemProcaryotic expression
Molecular weight42.3 kDa
Purity estimated80%
BufferPBS,pH 7.5
FormFrozen
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesEscherichia coli (E.coli)
Fragment TypePartial
Aliases /SynonymsNS1
ReferencePX-P3025
NoteFor research use only
Product nameZika virus NS1 Recombinant Protein
Origin speciesZika virus
Expression systemProcaryotic expression
Molecular weight42.3 kDa
Purity estimated80%
BufferPBS,pH 7.5
FormFrozen
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesEscherichia coli (E.coli)
Fragment TypePartial
Aliases /SynonymsNS1
ReferencePX-P3025
NoteFor research use only
Product nameZika virus NS1 Recombinant Protein
Origin speciesZika virus
Expression systemProcaryotic expression
Molecular weight42.3 kDa
Purity estimated80%
BufferPBS,pH 7.5
FormFrozen
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesEscherichia coli (E.coli)
Fragment TypePartial
Aliases /SynonymsNS1
ReferencePX-P3025
NoteFor research use only

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