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Vapaliximab Biosimilar – Anti-AOC3, VAP-1 mAb – Research Grade

Reference:
Size

100ug, 1MG

Isotype

IgG2, kappa

Brand

ProteoGenix

Product type

Primary Antibodies

Clonality

Monoclonal Antibody

Expression system

Mammalian cells

Applications

Elisa, WB

Product nameVapaliximab Biosimilar - Anti-AOC3, VAP-1 mAb - Research Grade
SourceCAS 336801-86-6
SpeciesChimeric
Expression systemMammalian cells
Purity>85%
BufferPBS buffer PH7.5
Delivery conditionBlue ice (+4°C)
Delivery Time3-5 days if in stock; 3-5 weeks if production needed
Storage conditionstore at -80°C
BrandProteoGenix
Aliases /SynonymsVapaliximab,2D10,AOC3, VAP-1,anti-AOC3, VAP-1
ReferencePX-TA1197
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG2-kappa
ClonalityMonoclonal Antibody

Description of Vapaliximab Biosimilar - Anti-AOC3, VAP-1 mAb - Research Grade

Introduction

Vapaliximab Biosimilar, also known as Anti-AOC3 or VAP-1 mAb, is a monoclonal antibody that has been developed as a biosimilar to the original drug Vapaliximab. This biosimilar is a promising therapeutic option for the treatment of various inflammatory and autoimmune diseases, as it targets a specific protein called AOC3. In this article, we will provide a scientific description of Vapaliximab Biosimilar in terms of its structure, activity, and potential applications.

Structure of Vapaliximab Biosimilar

Vapaliximab Biosimilar is a recombinant humanized monoclonal antibody that is produced using genetic engineering techniques. It is a protein molecule composed of two heavy chains and two light chains, connected by disulfide bonds. The heavy chains consist of constant and variable regions, while the light chains only have variable regions. The variable regions are responsible for binding to the target protein AOC3.

Activity of Vapaliximab Biosimilar

Vapaliximab Biosimilar is a highly specific antibody that targets the protein AOC3, also known as Vascular Adhesion Protein-1 (VAP-1). AOC3 is a cell surface enzyme that plays a crucial role in the inflammatory response and is involved in the development of various autoimmune diseases. By binding to AOC3, Vapaliximab Biosimilar blocks its activity and inhibits the recruitment of inflammatory cells to the site of inflammation.

Vapaliximab Biosimilar has been shown to have potent anti-inflammatory effects in preclinical studies. It has been found to reduce the production of pro-inflammatory cytokines and chemokines, as well as inhibit the adhesion and migration of immune cells. This makes it a promising therapeutic option for the treatment of a wide range of inflammatory and autoimmune diseases.

Potential Applications of Vapaliximab Biosimilar

Vapaliximab Biosimilar has shown promising results in preclinical studies for the treatment of various inflammatory and autoimmune diseases, including rheumatoid arthritis, psoriasis, and inflammatory bowel disease. It has also been evaluated in clinical trials for the treatment of diabetic retinopathy, a condition characterized by inflammation and abnormal blood vessel growth in the retina.

In addition to its potential as a therapeutic agent, Vapaliximab Biosimilar can also be used as a research tool to study the role of AOC3 in various diseases. By blocking the activity of AOC3, researchers can gain a better understanding of its role in the inflammatory response and its potential as a therapeutic target.

Conclusion

In summary, Vapaliximab Biosimilar, also known as Anti-AOC3 or VAP-1 mAb, is a recombinant humanized monoclonal antibody that specifically targets the protein AOC3. It has shown potent anti-inflammatory effects in preclinical studies and has the potential to be used as a therapeutic agent for various inflammatory and autoimmune diseases. In addition, it can also serve as a valuable research tool for studying the role of AOC3 in disease. Further clinical studies are needed to fully evaluate the efficacy and safety of Vapaliximab Biosimilar in treating inflammatory and autoimmune conditions.

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