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Brand: ProteoGenix

Ixekizumab Biosimilar – Anti-IL17A mAb – Research Grade

  • PX-TA1022-50
  • Validated ELISA FC WB
Clonality:
Monoclonal Antibody
Isotype:
IgG4, Kappa

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Ixekizumab Biosimilar - Anti-IL17A mAb - Research Grade

Product name Ixekizumab Biosimilar - Anti-IL17A mAb - Research Grade
Uniprot ID Q16552
Source DrugBank DB11569
Species Human
Expression system Mammalian cells
Raw Antigen Sequence MTPGKTSLVSLLLLLSLEAIVKAGITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA
Molecular weight 146kDa
Purity >85%
Buffer PBS pH7.5
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term; -20°C for long term
Brand ProteoGenix
Applications ELISA,WB
Aliases /Synonyms Ixekizumab,Ixekizumab,IL17A,anti-IL17A
Reference PX-TA1022
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG4Kappa
Clonality Monoclonal Antibody
Product name Ixekizumab Biosimilar - Anti-IL17A mAb - Research Grade
Uniprot ID Q16552
Source DrugBank DB11569
Species Human
Expression system Mammalian cells
Raw Antigen Sequence MTPGKTSLVSLLLLLSLEAIVKAGITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA
Molecular weight 146kDa
Purity >85%
Buffer PBS pH7.5
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term; -20°C for long term
Brand ProteoGenix
Applications ELISA,WB,,,
Aliases /Synonyms Ixekizumab,Ixekizumab,IL17A,anti-IL17A
Reference PX-TA1022
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG4Kappa
Clonality Monoclonal Antibody
Product name PX-TA1022-50
Uniprot ID Q16552
Source DrugBank DB11569
Species Human
Expression system Mammalian cells
Raw Antigen Sequence MTPGKTSLVSLLLLLSLEAIVKAGITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA
Molecular weight 146kDa
Purity >85%
Buffer PBS pH7.5
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term; -20°C for long term
Brand ProteoGenix
Aliases /Synonyms Ixekizumab,Ixekizumab,IL17A,anti-IL17A
Reference PX-TA1022
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG4, Kappa
Clonality Monoclonal Antibody

General information about Ixekizumab

Recombinant monoclonal antibody to IL17A. Ixekizumab is a humanized monoclonal antibody used in the treatment of autoimmune diseases. This product is for research use only.

SDS-PAGE for Ixekizumab Biosimilar - Anti-IL17A mAb

SDS-PAGE for Ixekizumab Biosimilar - Anti-IL17A mAb

Ixekizumab Biosimilar - Anti-IL17A mAb on SDS-PAGE under reducing (left figure) and non-reducing (right figure) conditions. The gel was stained overnight with Coomassie Blue. The purity of the antibody is superior than 90 %.

Ixekizumab Biosimilar - Anti-IL17A mAb binds to IL17A, C-His, recombinant protein in indirect ELISA Assay

Ixekizumab Biosimilar - Anti-IL17A mAb binds to IL17A, C-His, recombinant protein in indirect ELISA Assay

Immobilized IL17A, C-His, recombinant protein (cat. No.PX-P5780) at 0.5µg/mL (100µL/well) can bind to Ixekizumab Biosimilar - Anti-IL17A mAb (cat. No.PX-TA1022) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450

Flow Cytometry results for Ixekizumab Biosimilar - Anti-IL17A mAb - Research Grade

Flow Cytometry results for Ixekizumab Biosimilar - Anti-IL17A mAb - Research Grade

Flow-cytometry using anti-human IL17A antibody. Jurkat cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human IL17A monoclonal antibody (Catalog PX-TA1022, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: PTX18862) and cells analysed on a NovoCyte Flow Cytometer.

SEC-HPLC of Ixekizumab Biosimilar - Anti-IL17A mAb - Research Grade

SEC-HPLC of Ixekizumab Biosimilar - Anti-IL17A mAb - Research Grade

Ixekizumab Biosimilar - Anti-IL17A mAb - Research Grade was analyzed by size exclusion chromatography with UV detection.

Ixekizumab Biosimilar - Anti-IL17A mAb - Research Grade binds to Recombinant Mouse IL17A Protein, N-His in WB Assay

Ixekizumab Biosimilar - Anti-IL17A mAb - Research Grade binds to Recombinant Mouse IL17A Protein, N-His in WB Assay

Recombinant Mouse IL17A Protein, N-His(cat. No.ARO-P12452) can bind Ixekizumab Biosimilar - Anti-IL17A mAb - Research Grade in Western Blot Assay as detected on gel analysis.

Ixekizumab Biosimilar - Anti-IL17A mAb - Research Grade

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