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Brand: ProteoGenix

α/γ Antibody (Kwar23) Biosimilar – Anti-BIT mAb – Research Grade

Clonality:
Monoclonal Antibody
Isotype:
IgG1

200.00

100µg + 200 loyalty points
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α/γ Antibody (Kwar23) Biosimilar - Anti-BIT mAb - Research Grade

Product name α/γ Antibody (Kwar23) Biosimilar - Anti-BIT mAb - Research Grade
Species Homo sapiens
Buffer PBS buffer PH7.5
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3 week if production needed
Storage condition store at -80°C
Brand ProteoGenix
Applications ELISA,WB
Aliases /Synonyms anti-BIT, Signal-regulatory protein alpha-1, Brain Ig-like molecule with tyrosine-based activation motifs, MFR, SIRP, Sirp-alpha-1, Sirp-alpha-2, PTPNS1, SIRPA, SHP substrate 1, CD172 antigen-like family member A, Sirp-alpha-3, Inhibitory receptor SHPS-1, Signal-regulatory protein alpha-3, CD172a, Tyrosine-protein phosphatase non-receptor type substrate 1, MyD-1 antigen, Bit, SHPS-1, Macrophage fusion receptor, Signal-regulatory protein alpha-2, SHPS1, MYD1, p84,
Reference PX-TA1930
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG1 silence
Clonality Monoclonal Antibody
Product name α/γ Antibody (Kwar23) Biosimilar - Anti-BIT mAb - Research Grade
Species Homo sapiens
Expression system XtenCHO
Buffer PBS buffer PH7.5
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3 week if production needed
Storage condition store at -80°C
Brand ProteoGenix
Applications ELISA,WB,,,
Aliases /Synonyms anti-BIT, Signal-regulatory protein alpha-1, Brain Ig-like molecule with tyrosine-based activation motifs, MFR, SIRP, Sirp-alpha-1, Sirp-alpha-2, PTPNS1, SIRPA, SHP substrate 1, CD172 antigen-like family member A, Sirp-alpha-3, Inhibitory receptor SHPS-1, Signal-regulatory protein alpha-3, CD172a, Tyrosine-protein phosphatase non-receptor type substrate 1, MyD-1 antigen, Bit, SHPS-1, Macrophage fusion receptor, Signal-regulatory protein alpha-2, SHPS1, MYD1, p84,
Reference PX-TA1930
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG1 silence
Clonality Monoclonal Antibody

Title: Understanding the Structure and Function of α/γ Antibody (Kwar23) Biosimilar – Anti-BIT mAb – Research Grade

Introduction:

α/γ Antibody (Kwar23) Biosimilar – Anti-BIT mAb – Research Grade is a therapeutic antibody that has gained significant attention in the field of immunotherapy. This biosimilar is designed to target the B-cell immunoglobulin translocation (BIT) protein, which is a critical factor in the development and progression of various cancers. In this article, we will delve into the structure, activity, and potential applications of this biosimilar.

Structure of α/γ Antibody (Kwar23) Biosimilar:

The α/γ Antibody (Kwar23) Biosimilar is a monoclonal antibody that is produced by recombinant DNA technology. It consists of two identical heavy chains and two identical light chains, each with a molecular weight of approximately 150 kDa. The heavy chains are composed of four constant domains (CH1, CH2, CH3, and CH4) and one variable domain (VH), while the light chains consist of one constant domain (CL) and one variable domain (VL). The variable domains of both the heavy and light chains are responsible for binding to the target protein, BIT.

Activity of α/γ Antibody (Kwar23) Biosimilar:

The main mechanism of action of α/γ Antibody (Kwar23) Biosimilar is through its ability to bind to the BIT protein. This binding leads to the inhibition of the BIT signaling pathway, which is crucial for the growth and survival of cancer cells. By blocking this pathway, the biosimilar can effectively halt the proliferation and survival of cancer cells, making it a promising therapeutic option for various types of cancer.

Application of α/γ Antibody (Kwar23) Biosimilar:

The potential applications of α/γ Antibody (Kwar23) Biosimilar are vast, particularly in the field of oncology. This biosimilar has shown promising results in preclinical studies for the treatment of various cancers, including lymphoma, leukemia, and solid tumors. It has also been found to have synergistic effects when combined with other anti- cancer therapies, making it a potential candidate for combination therapy. Furthermore, the biosimilar has also shown efficacy in overcoming resistance to other targeted therapies, making it a valuable option for patients who have failed previous treatments.

Advantages of α/γ Antibody (Kwar23) Biosimilar:

One of the key advantages of α/γ Antibody (Kwar23) Biosimilar is its high specificity and selectivity towards the BIT protein. This allows for targeted therapy, minimizing the potential for off-target effects and reducing the risk of adverse reactions. Additionally, as a biosimilar, it is designed to have a similar structure and function to the original antibody, making it a more cost-effective treatment option compared to the original drug.

Conclusion:

In conclusion, α/γ Antibody (Kwar23) Biosimilar – Anti-BIT mAb – Research Grade is a promising therapeutic option for the treatment of various cancers. Its specific targeting of the BIT protein, along with its potential for combination therapy and overcoming resistance, makes it a valuable addition to the arsenal of anti- cancer therapies. With ongoing clinical trials and further research, this biosimilar has the potential to improve the lives of cancer patients and pave the way for more effective and targeted treatments.

SDS-PAGE for α/γ Antibody (Kwar23) Biosimilar - Anti-BIT mAb - Research Grade

SDS-PAGE for α/γ Antibody (Kwar23) Biosimilar - Anti-BIT mAb - Research Grade

α/γ Antibody (Kwar23) Biosimilar - Anti-BIT mAb - Research Grade on SDS-PAGE under reducing and non-reducing conditions. The gel was stained overnight with Coomassie Blue.. The purity of the antibody is greater than 95%.

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