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Co-inhibitory & Co-stimulatory receptors

Validated Reagents for Reliable Immune Checkpoint Research

Explore our validated range of primary antibodies, research-grade biosimilars and VHH antibodies targeting key co-inhibitory and co-stimulatory receptors, with products ready to ship.

Save 20% on this selection. Use code ONCO20. Valid until September 15

180 products
  • SDS-PAGE for Iscastobart Biosimilar - Research Grade

    Iscastobart Biosimilar - Research Grade

    • PX-TA2493
    Clonality:
    Monoclonal antibody
    Host species:
    Mammalian cells
    Isotype:
    IgG4, kappa
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Fetrastobart Biosimilar - Research Grade

    Fetrastobart Biosimilar - Research Grade

    • PX-TA2479
    Clonality:
    Monoclonal antibody
    Host species:
    Mammalian cells
    Isotype:
    IgG1, kappa
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Anti-Mouse CD152/CTLA4 Antibody (SAA2332)

    Anti-Mouse CD152/CTLA4 Antibody (SAA2332)

    • PTX27003
    Clonality:
    Monoclonal Antibody
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Anti-Human CD274/PD-L1/B7-H1 Antibody (22C3)

    Anti-Human CD274/PD-L1/B7-H1 Antibody (22C3)

    • PTX27041
    Clonality:
    Monoclonal Antibody
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Anti-Abatacept Antibody (SAA2444)

    Anti-Abatacept Antibody (SAA2444)

    • PTX27090
    Clonality:
    Polyclonal Antibody
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Anti-Mouse PD1 antibody(RMP1-14)

    Anti-Mouse PD1 antibody(RMP1-14)

    • ARO-A22612
    Clonality:
    Monoclonal Antibody
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Mouse CD223/LAG3 Recombinant Protein, C-Fc

    Mouse CD223/LAG3 Recombinant Protein, C-Fc

    • PX-P7031
    Host species:
    Mammalian cells
    Origin species:
    Mouse
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Abazistobart Biosimilar - Research Grade

    Abazistobart Biosimilar - Research Grade

    • PX-TA2424
    Clonality:
    Monoclonal antibody
    Host species:
    Mammalian cells
    Isotype:
    IgG4, Kappa
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Brivestobart Biosimilar - Research Grade

    Brivestobart Biosimilar - Research Grade

    • PX-TA2374
    Clonality:
    Monoclonal antibody
    Host species:
    Mammalian cells
    Isotype:
    IgG4, Kappa
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Alcestobart Biosimilar - Research Grade

    Alcestobart Biosimilar - Research Grade

    • PX-TA2373
    Clonality:
    Monoclonal antibody
    Host species:
    Mammalian cells
    Isotype:
    IgG4, Kappa
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Futermestotug Biosimilar - Research Grade

    Futermestotug Biosimilar - Research Grade

    • PX-TA2368
    Clonality:
    Monoclonal antibody
    Host species:
    Mammalian cells
    Isotype:
    IgG1, Kappa
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Sovipostobart beta Biosimilar - Research Grade

    Sovipostobart beta Biosimilar - Research Grade

    • PX-TA2367
    Clonality:
    Monoclonal antibody
    Host species:
    Mammalian cells
    Isotype:
    IgG1, Kappa
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Safimestomig Biosimilar - Research Grade

    Safimestomig Biosimilar - Research Grade

    • PX-TA2453
    Clonality:
    Monoclonal antibody
    Host species:
    Mammalian cells
    Isotype:
    IgG4, Kappa
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug
  • SDS-PAGE for Besufetamig Biosimilar - Research Grade

    Besufetamig Biosimilar - Research Grade

    • PX-TA2449
    • Validated WB
    Clonality:
    Monoclonal antibody
    Host species:
    Mammalian cells
    Isotype:
    IgG1, Kappa
    Brand:
    ProteoGenix
    Size:
    100ug, 1MG, 50ug

Co-inhibitory & Co-stimulatory Receptors

Researchers investigating immune regulation rely on co-inhibitory and co-stimulatory receptors to understand T cell activation, immune tolerance, cancer immunotherapy, autoimmune diseases, infectious diseases, and cell therapy development. Collectively, these molecules constitute the immune checkpoint pathways that regulate immune responses and have become central targets in immunology and immuno-oncology research.

ProteoGenix provides recombinant proteins and custom protein production services covering a broad range of immune checkpoint molecules and co-signaling receptors, supporting research from early discovery through preclinical development.

Top Products

Representative Immune Checkpoint Targets

Immune checkpoint research encompasses a broad network of co-inhibitory and co-stimulatory receptors involved in regulating immune activation and tolerance. Below is a representative selection of targets available through ProteoGenix.

Frequently studied co-inhibitory receptors

Frequently studied co-stimulatory receptors

Can’t find your target?

Not all immune checkpoint molecules are commercially available in the format required for your study. Our scientists can design and produce custom recombinant proteins, antibodies, Fc-fusion constructs, tagged proteins and engineered variants tailored to your experimental needs.

Explore Custom Protein Production

Supporting Every Stage of Immune Checkpoint Research

Whether your objective is basic immunology research or therapeutic development, selecting the appropriate recombinant protein is essential for obtaining reliable experimental results.

Our products are routinely used for applications including:

    • Receptor-ligand interaction studies
    • Antibody screening and characterization
    • ELISA development and validation
    • Surface Plasmon Resonance (SPR)
    • Bio-Layer Interferometry (BLI)
    • Cell-based functional assays
    • Flow cytometry assay development
    • Biomarker validation
    • Structural biology
    • Immunotherapy target evaluation
    • CAR-T and TCR research
    • Drug discovery programs

FAQ

Trusted Worldwide

Why Researchers Trust ProteoGenix

From validated reagents for co-signaling receptor research to custom antibody development, recombinant production and technical support, ProteoGenix helps researchers move faster from target selection to reliable experimental results.

  • Scientific & Technical Support

    Get expert support for product selection, format comparison, application fit and troubleshooting when your experiment requires more than a catalog search.

  • Quality Assurance

    Rigorous QC protocols with batch-specific certificates of analysis, lot-to-lot consistency, and ISO-certified manufacturing.

  • Custom Solutions

    From antibody production to protein expression, we offer end-to-end custom development tailored to your research objectives.

  • Global Delivery

    Reliable cold-chain logistics worldwide with temperature-controlled shipping and tracking for sensitive biological reagents.

Need a quote or more information? Contact us!

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