InVivo Plus Anti-Mouse CD279/PDCD1/PD1 Antibody (RMP1-14)

InVivo Plus Anti-Mouse CD279/PDCD1/PD1 Antibody (RMP1-14)

The Ultimate Tool for Immune Checkpoint Research

InVivo Plus Anti-Mouse CD279/PDCD1/PD1 Antibody (RMP1-14) is a highly specific and potent research tool designed for the study of immune checkpoint proteins. This antibody targets the mouse CD279 protein, also known as programmed cell death protein 1 (PD-1) or programmed death receptor 1 (PDCD1), which plays a crucial role in regulating immune responses.

Biological Function

CD279, or PD-1, is a transmembrane protein expressed on activated T cells, B cells, and myeloid cells. It acts as an immune checkpoint by binding to its ligands, PD-L1 and PD-L2, on antigen-presenting cells. This interaction inhibits T cell activation and prevents excessive immune responses, thus maintaining immune homeostasis.

Main Applications

InVivo Plus Anti-Mouse CD279/PDCD1/PD1 Antibody (RMP1-14) is an essential tool for researchers studying immune checkpoint pathways and their role in cancer, autoimmune diseases, and infectious diseases. It can also be used in preclinical studies to evaluate the efficacy of immune checkpoint inhibitors and potential therapeutic targets.

Experimental Use Cases

This antibody has been extensively validated for use in various experimental techniques, including flow cytometry, immunohistochemistry, and Western blotting. It has shown high specificity and sensitivity in detecting CD279 expression in mouse tissues and cells.

In flow cytometry, InVivo Plus Anti-Mouse CD279/PDCD1/PD1 Antibody (RMP1-14) can be used to analyze PD-1 expression on different immune cell subsets and evaluate its modulation in response to various stimuli. In immunohistochemistry, it enables visualization and localization of PD-1 expression in tissue sections. And in Western blotting, it can be used to detect the presence of PD-1 protein in cell lysates.

InVivo Plus Anti-Mouse CD279/PDCD1/PD1 Antibody (RMP1-14) is a reliable and high-quality research tool that provides accurate and reproducible results, making it an ideal choice for any immune checkpoint-related study.

In summary, InVivo Plus Anti-Mouse CD279/PDCD1/PD1 Antibody (RMP1-14) is a powerful tool for investigating the role of PD-1 in immune regulation and its potential as a therapeutic target. With its impressive performance and versatility, this antibody is a must-have for any researcher working in the field of immune checkpoint research. Order now and take your research to the next level!