Sclerostin (SOST )

Reference:
Size

100ug, 50ug

Brand

Product type

Host Species

Applications

,

Product nameSclerostin (SOST )
Uniprot IDQ9BQB4
Uniprot linkhttp://www.uniprot.org/uniprot/Q9BQB4
Expression systemProkaryotic expression
SequenceMGHHHHHHMSDSEVNQEAKPEVKPEVKPETHINLKVSDGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIGGQGSQGWQAFKNDATEIIPELGEYPEPPPELENNKTMNRAENGGRPPHHPFETKDVSEYSCRELHFTRYVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRGKWWRPSGPDFRCIPDRYRAQRVQLLCPGGEAPRARKVRLVASCKCKRLTRFHNQSELKDFGTEAARPQKGRKPRPRARSAKANQAELENAY
Purity estimated>40%by SDS-PAGE
BufferPBS, pH7.5
Delivery conditionDry Ice
Delivery lead time in business daysEurope: 5-7 working days
USA & Canada: 7-10 working days
Rest of the world: 5-12 working days
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesEscherichia coli (E.coli)
ApplicationsELISA,WB
Fragment TypeGln24-Tyr213
Aliases /SynonymsSclerostin
ReferencePX-P4621
NoteFor research use only

Description of Sclerostin (SOST )

General Information about Sclerostin (SOST)

Sclerostin is a protein encoded by the SOST gene in humans. Sclerostin is a secreted glycoprotein with a C-terminal cysteine ​​knot-like (CTCK) domain, and its sequence is different from that of the bone morphogenetic protein (BMP) antagonist DAN (differential selection gene in neuroblastoma) . Sclerostin is mainly produced by bone cells, but it can also be expressed in other tissues and has an anti-anabolic effect on bone formation.

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