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Nipocalimab Biosimilar – Anti-FCGRT mAb – Research Grade

Reference:
Size

100ug, 1MG

Isotype

IgG1, lambda

Brand

ProteoGenix

Product type

Primary Antibodies

Clonality

Monoclonal Antibody

Expression system

XtenCHO

Applications

Elisa, WB

Product nameNipocalimab Biosimilar - Anti-FCGRT mAb - Research Grade
SourceCAS 2211985-36-1
SpeciesHomo sapiens
Expression systemXtenCHO
Purity>85%
BufferPBS buffer PH7.5
Delivery conditionBlue ice (+4°C)
Delivery Time3-5 days if in stock; 3 week if production needed
Storage conditionstore at -80°C
BrandProteoGenix
Aliases /SynonymsNipocalimab,IMMUNOGLOBULIN G1, ANTI-(HUMAN NEONATAL FC RECEPTOR) (HUMAN MONOCLONAL M281 .GAMMA.-1 CHAIN), DISULFIDE WITH HUMAN MONOCLONAL M281 .LAMBDA.-CHAIN, DIMER, M-281,FCGRT,anti-FCGRT
ReferencePX-TA1690
NoteFor research use only. Not suitable for clinical or therapeutic use.
IsotypeIgG1,Lambda
ClonalityMonoclonal Antibody

Description of Nipocalimab Biosimilar - Anti-FCGRT mAb - Research Grade

Nipocalimab Biosimilar – Anti-FCGRT mAb – Research Grade

Nipocalimab Biosimilar – Anti-FCGRT mAb – Research Grade: A Revolutionary Antibody Nipocalimab Biosimilar, also known as Anti-FCGRT mAb, is a groundbreaking antibody that has the potential to revolutionize the field of therapeutics. This biosimilar is a monoclonal antibody that specifically targets the FCGRT protein, making it a highly specific and effective therapeutic agent.

Structure of Nipocalimab Biosimilar

Nipocalimab Biosimilar is a recombinant humanized IgG1 monoclonal antibody. It is composed of two heavy chains and two light chains, making it a Y-shaped molecule. The heavy chains consist of four constant regions (CH1, CH2, CH3, and CH4) and one variable region (VH). The light chains consist of one constant region (CL) and one variable region (VL). These variable regions are responsible for the specific binding to the FCGRT protein.

Activity of Nipocalimab Biosimilar

The main activity of Nipocalimab Biosimilar is its ability to bind to the FCGRT protein. FCGRT, also known as neonatal Fc receptor, is a protein that plays a crucial role in the recycling of immunoglobulin G (IgG) antibodies in the body. By binding to FCGRT, Nipocalimab Biosimilar blocks the recycling of IgG antibodies, leading to a decrease in their levels in the body. This, in turn, can have a therapeutic effect on various diseases.

Application of Nipocalimab Biosimilar

Nipocalimab Biosimilar has shown promising results in preclinical studies for the treatment of various diseases. Its main application is in the treatment of autoimmune diseases, such as rheumatoid arthritis, lupus, and multiple sclerosis. By reducing the levels of IgG antibodies, Nipocalimab Biosimilar can help alleviate the symptoms of these diseases and improve the overall health of patients.

Additionally, Nipocalimab Biosimilar has also shown potential in the treatment of cancer. By targeting the FCGRT protein, it can enhance the body’s immune response against cancer cells and potentially improve the efficacy of other cancer therapies.

Benefits of Nipocalimab Biosimilar

Nipocalimab Biosimilar has several advantages over traditional therapies. Firstly, its highly specific binding to the FCGRT protein minimizes the risk of off-target effects and reduces the potential for adverse reactions. Secondly, as a biosimilar, it is a more cost-effective option compared to other monoclonal antibodies on the market. Finally, its potential to treat a wide range of diseases makes it a versatile and valuable therapeutic agent.

Future of Nipocalimab Biosimilar

The future of Nipocalimab Biosimilar looks promising, with ongoing clinical trials in various autoimmune diseases and cancer. If successful, it has the potential to become a game-changer in the field of therapeutics, providing a more targeted and cost-effective treatment option for patients.

Conclusion

Nipocalimab Biosimilar, also known as Anti-FCGRT mAb, is a highly specific and effective antibody that targets the FCGRT protein. Its potential to treat various diseases, along with its cost-effectiveness, make it a promising therapeutic option for patients. With ongoing research and clinical trials, Nipocalimab Biosimilar has the potential to revolutionize the field of therapeutics and improve the lives of many individuals.

SDS-PAGE for Nipocalimab Biosimilar - Anti-FCGRT mAb

Nipocalimab Biosimilar - Anti-FCGRT mAb, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.

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