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Brand: ProteoGenix

Nesvacumab Biosimilar – Anti-ANGPT2 mAb – Research Grade

Clonality:
Monoclonal Antibody
Isotype:
IgG1-nd

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Nesvacumab Biosimilar - Anti-ANGPT2 mAb binds to Humand ANGPT2 in indirect ELISA Assay
Nesvacumab Biosimilar - Anti-ANGPT2 mAb - Research Grade

Nesvacumab Biosimilar - Anti-ANGPT2 mAb - Research Grade

Product name Nesvacumab Biosimilar - Anti-ANGPT2 mAb - Research Grade
Uniprot ID O15123
Source CAS 1296818-77-3
Species Homo sapiens
Expression system Mammalian cells
Raw Antigen Sequence MWQIVFFTLSCDLVLAAAYNNFRKSMDSIGKKQYQVQHGSCSYTFLLPEMDNCRSSSSPYVSNAVQRDAPLEYDDSVQRLQVLENIMENNTQWLMKLENYIQDNMKKEMVEIQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQLLEHSLSTNKLEKQILDQTSEINKLQDKNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQVLVSKQNSIIEELEKKIVTATVNNSVLQKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF
Purity >85%
Buffer PBS buffer PH7.5
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition store at -80°C
Brand ProteoGenix
Applications ELISA,WB
Aliases /Synonyms Nesvacumab,REGN-910,ANGPT2,anti-ANGPT2
Reference PX-TA1311
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG1-nd
Clonality Monoclonal Antibody
Product name Nesvacumab Biosimilar - Anti-ANGPT2 mAb - Research Grade
Uniprot ID O15123
Source CAS 1296818-77-3
Species Homo sapiens
Expression system Mammalian cells
Raw Antigen Sequence MWQIVFFTLSCDLVLAAAYNNFRKSMDSIGKKQYQVQHGSCSYTFLLPEMDNCRSSSSPYVSNAVQRDAPLEYDDSVQRLQVLENIMENNTQWLMKLENYIQDNMKKEMVEIQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQLLEHSLSTNKLEKQILDQTSEINKLQDKNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQVLVSKQNSIIEELEKKIVTATVNNSVLQKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF
Purity >85%
Buffer PBS buffer PH7.5
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition store at -80°C
Brand ProteoGenix
Applications ELISA,WB,,,
Aliases /Synonyms Nesvacumab,REGN-910,ANGPT2,anti-ANGPT2
Reference PX-TA1311
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG1-nd
Clonality Monoclonal Antibody
Product name PX-TA1311-50
Uniprot ID O15123
Source CAS 1296818-77-3
Species Homo sapiens
Expression system Mammalian cells
Raw Antigen Sequence MWQIVFFTLSCDLVLAAAYNNFRKSMDSIGKKQYQVQHGSCSYTFLLPEMDNCRSSSSPYVSNAVQRDAPLEYDDSVQRLQVLENIMENNTQWLMKLENYIQDNMKKEMVEIQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQLLEHSLSTNKLEKQILDQTSEINKLQDKNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQVLVSKQNSIIEELEKKIVTATVNNSVLQKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF
Purity >85%
Buffer PBS buffer PH7.5
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition store at -80°C
Brand ProteoGenix
Aliases /Synonyms Nesvacumab,REGN-910,ANGPT2,anti-ANGPT2
Reference PX-TA1311
Note For research use only. Not suitable for human use.
Isotype IgG1-nd
Clonality Monoclonal Antibody

General information on Anti-ANGPT2[Homo sapiens] (Nesvacumab) Monoclonal Antibody

Nesvacumab is investigated for the treatment of Neovascular (Wet) Age Related Macular Degeneration (AMD) or Diabetic Macular Edema (DME).

Nesvacumab Biosimilar - Anti-ANGPT2 mAb binds to Humand ANGPT2 in indirect ELISA Assay

Nesvacumab Biosimilar - Anti-ANGPT2 mAb binds to Humand ANGPT2 in indirect ELISA Assay

Immobilized Human ANGPT2-Ang2 recombinant protein (cat. No.PX-P6245) at 0.5µg/mL (100µL/well) can bind Nesvacumab Biosimilar - Anti-ANGPT2 mAb (cat. No.PX-TA1311) in indirect ELISA with Goat Anti-human IgG secondary antibody coupled with HRP measured by OD450 giving an EC50 at 16.93M.

Nesvacumab Biosimilar - Anti-ANGPT2 mAb - Research Grade

  • Sim, M., Ohnuki, H., Durell, S. et al. Angiopoietin-2 binds to FGFR2, inhibits FGF-FGFR2 signaling, and delays cutaneous wound healing by inhibiting wound angiogenesis. Angiogenesis 28, 43 (2025). https://doi.org/10.1007/s10456-025-09988-2

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