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Thioredoxin reductase 1, cytoplasmic(TXNRD1)(Mammalian cells production)
| size | 100ug, 50ug |
|---|---|
| Brand | ProteoGenix |
| Product type | Recombinant Proteins |
| Host Species | Mammalian cells |
| Applications | Elisa, WB |
| Product name | Thioredoxin reductase 1, cytoplasmic(TXNRD1)(Mammalian cells production) |
|---|---|
| Uniprot ID | Q16881 |
| Uniprot link | http://www.uniprot.org/uniprot/Q16881 |
| Expression system | Eukaryotic expression |
| Sequence | MGCAEGKAVAAAAPTELQTKGKNGDGRRRSAKDHHPGKTLPENPAGFTSTATADSRALLQAYIDGHSVVIFSRSTCTRCTEVKKLFKSLCVPYFVLELDQTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGCCGSHHHHHH |
| Purity estimated | >85% by SDS-PAGE |
| Buffer | PBS, pH7.5 |
| Delivery condition | Dry Ice |
| Delivery lead time in business days | Europe: 5-7 working days USA & Canada: 7-10 working days Rest of the world: 5-12 working days |
| Storage condition | 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection) |
| Brand | ProteoGenix |
| Host species | Mammalian cells |
| Fragment Type | Met1-Cys647 |
| Aliases /Synonyms | TR,Gene associated with retinoic and interferon-induced mortality 12 protein,GRIM-12,Gene associated with retinoic and IFN-induced mortality 12 protein,KM-102-derived reductase-like factor,Thioredoxin reductase TR1,GRIM12, KDRF |
| Reference | PX-P4610 |
| Note | For research use only |
Description of Thioredoxin reductase 1, cytoplasmic(TXNRD1)(Mammalian cells production)
General Information about Thioredoxin reductase 1, cytoplasmic (TXNRD1)
Thioredoxin reductase 1 (cytoplasm) is an enzyme in humans encoded by the TXNRD1 gene, which encodes a member of the pyridine nucleotide oxidoreductase family. The protein can reduce thioredoxin and other substrates, and play a role in selenium metabolism and anti-oxidative stress. This functional enzyme is considered to be a homodimer using FAD as a cofactor. Each subunit contains selenocysteine (Sec), which is necessary for catalytic activity. Selenocysteine is encoded by the UGA codon which normally signals the termination of translation. The 3′ UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
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