The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Brand
ProteoGenix
Size
96T
Reference
KPTX245
Note
For research use only.
Sample type
Plasma, Serum
Immunogen
Simlukafusp Alfa
Description of Simlukafusp Alfa ELISA Kit
Introduction to Simlukafusp Alfa ELISA Kit
The Simlukafusp Alfa ELISA Kit is a highly sensitive and accurate diagnostic tool used in the detection and quantification of Simlukafusp Alfa, a fusion protein used as a therapeutic agent in the treatment of certain types of cancer. This kit is specifically designed for the detection of Simlukafusp Alfa in biological samples, making it a valuable tool for researchers and clinicians alike.
Structure of Simlukafusp Alfa
Simlukafusp Alfa is a fusion protein composed of two distinct components the Simian Immunodeficiency Virus (SIV) envelope protein gp120 and the humanized anti-CD3 antibody hOKT3?1 (also known as Alfa). The gp120 component is responsible for targeting the protein to CD4+ T cells, while the hOKT3?1 component binds to the CD3 receptor on these cells, leading to their activation and subsequent destruction. This unique structure allows Simlukafusp Alfa to specifically target and eliminate cancer cells, making it a promising therapeutic agent.
Activity of Simlukafusp Alfa
The activity of Simlukafusp Alfa is based on its ability to selectively target and bind to CD4+ T cells, which are often overexpressed in certain types of cancer. The gp120 component of the fusion protein binds to the CD4 receptor on these cells, while the hOKT3?1 component binds to the CD3 receptor. This dual binding leads to the activation of the CD4+ T cells, causing them to release cytotoxic substances that can destroy cancer cells. This targeted approach minimizes the potential side effects of traditional cancer treatments, making Simlukafusp Alfa a promising therapeutic option.
Application of Simlukafusp Alfa ELISA Kit
The Simlukafusp Alfa ELISA Kit is a valuable tool for researchers and clinicians involved in the development and use of Simlukafusp Alfa as a therapeutic agent. This kit allows for the accurate and sensitive detection of Simlukafusp Alfa in biological samples, such as blood or tissue samples, providing crucial information on the levels of the fusion protein in a patient’s body. This information can be used to monitor the effectiveness of treatment, as well as to assess potential side effects.
Additionally, the Simlukafusp Alfa ELISA Kit can also be used in preclinical studies to evaluate the pharmacokinetics and pharmacodynamics of Simlukafusp Alfa, providing important data for the development of new treatment strategies. The kit can also be used in the screening of potential therapeutic agents that may interact with Simlukafusp Alfa, aiding in the development of combination therapies.
Conclusion
The Simlukafusp Alfa ELISA Kit is an essential tool for the detection and quantification of Simlukafusp Alfa in biological samples. Its high sensitivity and accuracy make it a valuable asset in the development and use of this promising fusion protein as a therapeutic agent in the treatment of cancer. With its ability to provide crucial information on Simlukafusp Alfa levels in a patient’s body, this kit is a crucial tool in the fight against cancer.
Keywords: Simlukafusp Alfa, ELISA Kit, fusion protein, therapeutic agent, CD4+ T cells, cancer treatment, pharmacokinetics, pharmacodynamics, combination therapy
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