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Brand: ProteoGenix

SIGLEC2 recombinant protein

Host species:
Escherichia coli (E.coli)
Origin species:
Homo sapiens (Human)
Molecular weight:
19.57 kDa

329.00

100ug + 329 loyalty points
His Trp176–Ala330
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SIGLEC2 recombinant protein

Product name SIGLEC2 recombinant protein
Uniprot link https://www.uniprot.org/uniprot/P20273
Origin species Homo sapiens (Human)
Expression system Prokaryotic expression
Molecular weight 19.57 kDa
Protein delivered with Tag? N-terminal His Tag
Purity estimated >90% as determined by SDS-PAGE
Buffer PBS, pH7.5
Delivery condition Dry Ice
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Escherichia coli (E.coli)
Fragment Type Trp176-Ala330
Protein Accession P20273
Aliases /Synonyms Sialic acid-binding Ig-like lectin 2, Siglec-2, CD22, T-cell surface antigen Leu-14, BL-CAM, B-lymphocyte cell adhesion molecule, B-cell receptor CD22
Reference PX-P5177
Note For research use only
Background information Array
Molecular Constructor
His Trp176–Ala330

General information on SIGLEC2 recombinant protein

SIGLEC2 Recombinant Protein: Structure and Activity

SIGLEC2 is a member of the CD family of proteins, which are transmembrane receptors that recognize and bind to the sialic acid molecules found on the surface of cells. SIGLEC2 is expressed on the surface of B cells, monocytes, and macrophages, and is involved in immune cell signaling and regulation. The recombinant form of SIGLEC2 is a soluble protein that has been overexpressed in a recombinant expression system. This protein contains a single transmembrane domain and an extracellular domain, which is composed of two immunoglobulin-like domains.

SIGLEC2 Recombinant Protein: Application

The recombinant form of SIGLEC2 can be used in a variety of research applications, including functional assays, immunoassays, and antibody-drug target studies. In functional assays, the recombinant protein can be used to study the interactions between SIGLEC2 and its ligands, such as sialic acid. In immunoassays, the protein can be used to detect and quantify the presence of SIGLEC2 on the surface of cells. Finally, the recombinant protein can be used in antibody-drug target studies to investigate the potential of SIGLEC2 as a therapeutic target.

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