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View ProductsBrand | ProteoGenix |
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Product type | Elisa assay kits |
Size | 96T |
Product name | Oleclumab ELISA Kit |
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Delivery condition | Blue ice (+4°) |
Storage condition | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
Brand | ProteoGenix |
Size | 96T |
Reference | KPTX207 |
Note | For research use only. |
Sample type | Plasma, Serum |
Immunogen | Oleclumab |
Oleclumab ELISA Kit is a powerful tool used in the field of immunology for the detection and quantification of Oleclumab, a monoclonal antibody that specifically targets the programmed death ligand 1 (PD-L1) protein. This kit is widely used in research and clinical settings to study the structure, activity, and application of Oleclumab in various disease states. In this article, we will discuss the key features of the Oleclumab ELISA Kit and its importance in understanding the role of PD-L1 in immune regulation and disease progression.
Oleclumab is a fully humanized IgG4 monoclonal antibody that binds to PD-L1 with high affinity and specificity. It is composed of two heavy chains and two light chains, each containing unique variable regions that determine its binding specificity. The variable regions of Oleclumab are derived from human B-cells, making it less immunogenic and more suitable for therapeutic use.
The main function of Oleclumab is to block the interaction between PD-L1 and its receptor, programmed cell death protein 1 (PD-1). This interaction is a key mechanism used by cancer cells and other immune cells to evade the immune system and promote tumor growth. By inhibiting this interaction, Oleclumab enhances the anti-tumor activity of immune cells, leading to tumor regression and improved patient outcomes.
The activity of Oleclumab can be measured using the Oleclumab ELISA Kit, which detects the levels of free and bound Oleclumab in biological samples. This allows researchers to monitor the pharmacokinetics of Oleclumab and assess its efficacy in clinical trials.
The Oleclumab ELISA Kit has a wide range of applications in both research and clinical settings. Some of the key applications include:
The Oleclumab ELISA Kit is a valuable tool for studying the structure, activity, and application of Oleclumab in various disease states. Its ability to accurately detect and quantify Oleclumab levels makes it an essential tool for drug development, biomarker discovery, and disease monitoring. With the growing interest in immunotherapy and the use of monoclonal antibodies, the Oleclumab ELISA Kit will continue to play a crucial role in advancing our understanding of the immune system and its role in disease.
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