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Brand: ProteoGenix

Obinutuzumab Biosimilar – Anti-MS4A1, CD20 mAb – Research Grade

Clonality:
Monoclonal Antibody
Isotype:
IgG1, kappa

€200.00

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Obinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade binds to Human CD20/MS4A1 recombinant protein in ELISA assay
SDS-PAGE for Obinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade

Obinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade

Product name Obinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade
Source CAS 949142-50-1
Species Humanized
Molecular weight 150kDa
Purity >85%
Buffer PBS buffer PH7.5
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition store at -80°C
Brand ProteoGenix
Applications ELISA,WB
Aliases /Synonyms Obinutuzumab,GA101,RG7159,RO5072759,afutuzumab,MS4A1, CD20,anti-MS4A1, CD20
Reference PX-TA1172
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG1-kappa
Clonality Monoclonal Antibody
Product name Obinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade
Source CAS 949142-50-1
Species Humanized
Expression system Mammalian cells
Molecular weight 150kDa
Purity >85%
Buffer PBS buffer PH7.5
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition store at -80°C
Brand ProteoGenix
Applications ELISA,WB,,,
Aliases /Synonyms Obinutuzumab,GA101,RG7159,RO5072759,afutuzumab,MS4A1, CD20,anti-MS4A1, CD20
Reference PX-TA1172
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG1-kappa
Clonality Monoclonal Antibody

General information on Anti-MS4A1/CD20(Homo sapiens) (Obinutuzumab) Monoclonal Antibody

Obinutuzumab is a humanized monoclonal antibody that can be used in combination with chlorambucil to treat chronic lymphocytic leukemia. It was sold under the Gazyva brand. There are black box warnings of fatal hepatitis B virus (HBV) reactivation and fatal progressive multifocal leukoencephalopathy (PML).

Obinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade binds to Human CD20/MS4A1 recombinant protein in ELISA assay

Obinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade binds to Human CD20/MS4A1 recombinant protein in ELISA assay

Immobilized Human CD20/MS4A1 recombinant protein (cat. No.PX-P6274) at 0.5µg/mL (100µL/well) can bind Obinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade (cat. No.PX-TA1172) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450 giving an EC50 at 134.2M.

SDS-PAGE for Obinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade

SDS-PAGE for Obinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade

Obinutuzumab Biosimilar - Anti-MS4A1, CD20 mAb - Research Grade on SDS-PAGE under reducing and non-reducing conditions. The gel was stained overnight with Coomassie Blue.. The purity of the antibody is greater than 95%.

  • Joshua S. Bray, Gethin R. Thomas, Victoria M. Smith, Sandrine Jayne, Martin J.S. Dyer, Harriet S. Walter, Comparative in-Vitro Efficacy of CD20xCD3 IgG Bispecific Biosimilar Constructs Against Diffuse Large B Cell Lymphoma (DLBCL) Cell Lines with Different Levels of Expression of CD20, Blood, Volume 144, Supplement 1, 2024, Page 5826, ISSN 0006-4971, https://doi.org/10.1182/blood-2024-203884.

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