Uliledlimab Biosimilar – Anti-NT5E mAb – Research Grade

Description of Uliledlimab Biosimilar - Anti-NT5E mAb - Research Grade

Introduction

Uliledlimab Biosimilar, also known as Anti-NT5E mAb, is a monoclonal antibody that targets the enzyme CD73, also known as NT5E. This enzyme is involved in the production of adenosine, a molecule that plays a key role in regulating the immune response. By inhibiting CD73, Uliledlimab Biosimilar has the potential to modulate the immune system and treat various diseases. In this article, we will explore the structure, activity, and potential applications of Uliledlimab Biosimilar as a research grade antibody.

Structure of Uliledlimab Biosimilar

Uliledlimab Biosimilar is a fully human monoclonal antibody, meaning it is derived from human cells and has a high level of specificity and affinity for its target. It is composed of two identical heavy chains and two identical light chains, each containing a variable region that binds specifically to CD73. The structure of Uliledlimab Biosimilar is similar to that of other therapeutic antibodies, with a Y-shaped structure and a flexible hinge region that allows for binding to multiple targets.

Activity of Uliledlimab Biosimilar

The main activity of Uliledlimab Biosimilar is its ability to inhibit the activity of CD73. This enzyme is expressed on the surface of various immune cells, including T cells, B cells, and natural killer cells. CD73 is responsible for converting extracellular ATP to adenosine, which has immunosuppressive effects. By inhibiting CD73, Uliledlimab Biosimilar can prevent the production of adenosine and potentially enhance the immune response.

Additionally, Uliledlimab Biosimilar has been shown to have anti-inflammatory effects by reducing the production of pro-inflammatory cytokines and chemokines. This activity has been demonstrated in various pre-clinical studies, making Uliledlimab Biosimilar a promising candidate for the treatment of inflammatory diseases.

Potential Applications of Uliledlimab Biosimilar

As a research grade antibody, Uliledlimab Biosimilar has the potential to be used in a variety of studies and experiments. Its main application is in the field of immunology, where it can be used to investigate the role of CD73 in the immune response and its potential as a therapeutic target.

Uliledlimab Biosimilar may also have potential applications in the treatment of various diseases. Its ability to modulate the immune response could make it a valuable tool in the treatment of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Additionally, its anti-inflammatory effects could be beneficial in the treatment of inflammatory conditions, such as asthma and inflammatory bowel disease.

Furthermore, Uliledlimab Biosimilar has shown promising results in pre-clinical studies for the treatment of cancer. By inhibiting CD73, it can prevent the production of adenosine, which is known to suppress the immune response against tumors. This makes Uliledlimab Biosimilar a potential candidate for combination therapy with other cancer treatments.

Conclusion

In summary, Uliledlimab Biosimilar is a monoclonal antibody that targets CD73 and has the potential to modulate the immune response and treat various diseases. Its structure, activity, and potential applications make it a valuable tool for research and a promising candidate for therapeutic use. Further studies and clinical trials are needed to fully understand the potential of Uliledlimab Biosimilar as a therapeutic antibody.

SDS-PAGE for Uliledlimab Biosimilar - Anti-NT5E mAb

Uliledlimab Biosimilar - Anti-NT5E mAb, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.