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| Size | 100ug, 1MG |
|---|---|
| Isotype | IgG4, kappa |
| Brand | ProteoGenix |
| Product type | Primary Antibodies |
| Clonality | Monoclonal Antibody |
| Expression system | XtenCHO |
| Applications | Elisa, WB |
| Product name | Rolistobart Biosimilar - Anti-CD85 antigen-like family member K mAb - Research Grade |
|---|---|
| Source | CAS: 2723442-10-0 |
| Species | Human |
| Expression system | XtenCHO |
| Buffer | 0.01M PBS, pH 7.4 |
| Delivery condition | Blue ice (+4°C) |
| Delivery Time | 3-5 days if in stock; 3 week if production needed |
| Storage condition | store at -80°C |
| Brand | ProteoGenix |
| Aliases /Synonyms | anti-CD85 antigen-like family member K, LIR-5, Leukocyte immunoglobulin-like receptor 5, ILT3, ILT-3, Immunoglobulin-like transcript 3, LILRB4, CD85k, Leukocyte immunoglobulin-like receptor subfamily B member 4, Monocyte inhibitory receptor HM18, LIR5 |
| Reference | PX-TA1971 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype | IgG4, Kappa |
| Clonality | Monoclonal Antibody |
Rolistobart Biosimilar – Anti-CD85 antigen-like family member K mAb – Research Grade is a monoclonal antibody that has been developed as a biosimilar to treat various diseases. This antibody specifically targets the CD85 antigen-like family member K (CD85K), which is a protein that plays a crucial role in regulating the immune system. In this article, we will discuss the structure, activity, and potential applications of this biosimilar in the field of medicine.
Rolistobart Biosimilar is a monoclonal antibody, which means it is derived from a single type of immune cell. It is a recombinant antibody, meaning it is produced using genetic engineering techniques. This biosimilar has a similar structure to the reference product, which is the original antibody it is based on. The structure of Rolistobart Biosimilar includes two heavy chains and two light chains, which are connected by disulfide bonds. These chains are made up of amino acids and are responsible for the antibody’s binding specificity and function.
The main activity of Rolistobart Biosimilar is its ability to bind to the CD85K protein. This protein is found on the surface of various immune cells, including natural killer (NK) cells, T cells, and B cells. By binding to CD85K, the biosimilar can modulate the immune response and potentially treat diseases where the immune system is overactive or underactive.
In addition to its binding activity, Rolistobart Biosimilar also has a mechanism of action known as antibody-dependent cell-mediated cytotoxicity (ADCC). This means that the antibody can activate immune cells, such as NK cells, to attack and destroy target cells that express the CD85K protein. This activity is particularly relevant in the treatment of cancer, where the antibody can help the immune system to recognize and eliminate cancer cells.
Rolistobart Biosimilar has potential applications in various fields of medicine, including oncology, immunology, and infectious diseases. In oncology, the biosimilar can be used to treat various types of cancer that overexpress CD85K, such as lymphoma, leukemia, and solid tumors. By targeting CD85K, the antibody can help to inhibit the growth and spread of cancer cells and potentially improve patient outcomes.
In the field of immunology, Rolistobart Biosimilar can be used to treat autoimmune diseases, where the immune system mistakenly attacks healthy cells and tissues. By targeting CD85K, the biosimilar can help to regulate the immune response and reduce inflammation, which is a hallmark of autoimmune diseases.
Furthermore, Rolistobart Biosimilar can also be used in infectious diseases, particularly those caused by viruses. This is because CD85K has been shown to play a role in viral infections, and by targeting this protein, the biosimilar can potentially prevent viral replication and spread.
In summary, Rolistobart Biosimilar – Anti-CD85 antigen-like family member K mAb – Research Grade is a monoclonal antibody that specifically targets the CD85K protein. Its structure, activity, and potential applications make it a promising biosimilar in the field of medicine. With further research and development, this biosimilar has the potential to improve patient outcomes and provide a more cost-effective treatment option for various diseases.
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