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Brand: ProteoGenix

Reslizumab Biosimilar – Anti-IL5 mAb – Research Grade

  • PX-TA1198-50
  • Validated ELISA
Clonality:
Monoclonal Antibody
Isotype:
IgG4-nd

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Reslizumab Biosimilar - Anti-IL5 mAb - Research Grade

Product name Reslizumab Biosimilar - Anti-IL5 mAb - Research Grade
Uniprot ID P05113
Source CAS 241473-69-8
Species Humanized
Expression system Mammalian cells
Raw Antigen Sequence MRMLLHLSLLALGAAYVYAIPTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNHQLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQEFLGVMNTEWIIES
Purity >85%
Buffer PBS buffer PH7.5
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition store at -80°C
Brand ProteoGenix
Applications ELISA,WB
Aliases /Synonyms Reslizumab,CDP-835,JES1-39D10,SCH55700,IL5,anti-IL5
Reference PX-TA1198
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG4-nd
Clonality Monoclonal Antibody
Product name Reslizumab Biosimilar - Anti-IL5 mAb - Research Grade
Uniprot ID P05113
Source CAS 241473-69-8
Species Humanized
Expression system Mammalian cells
Raw Antigen Sequence MRMLLHLSLLALGAAYVYAIPTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNHQLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQEFLGVMNTEWIIES
Purity >85%
Buffer PBS buffer PH7.5
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition store at -80°C
Brand ProteoGenix
Applications ELISA,WB,,,
Aliases /Synonyms Reslizumab,CDP-835,JES1-39D10,SCH55700,IL5,anti-IL5
Reference PX-TA1198
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG4-nd
Clonality Monoclonal Antibody
Product name PX-TA1198-50
Uniprot ID P05113
Source CAS 241473-69-8
Species Humanized
Expression system Mammalian cells
Raw Antigen Sequence MRMLLHLSLLALGAAYVYAIPTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNHQLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQEFLGVMNTEWIIES
Purity >85%
Buffer PBS buffer PH7.5
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition store at -80°C
Brand ProteoGenix
Aliases /Synonyms Reslizumab,CDP-835,JES1-39D10,SCH55700,IL5,anti-IL5
Reference PX-TA1198
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG4-nd
Clonality Monoclonal Antibody

General information on Anti-IL5(Homo sapiens) (Reslizumab) Monoclonal Antibody

Reslizumab is a humanized interleukin 5 (IL-5) antagonist monoclonal antibody (IgG4 kappa), produced by recombinant DNA technology in murine non-secretory myeloma 0 (NS0) cells. IL-5 is a pro-inflammatory cytokine responsible for the growth and differentiation, recruitment, activation and survival of eosinophil markers. Elevated levels of eosinophils increase the risk of exacerbation of asthma, including allergic and non-allergic forms of asthma characterized by eosinophilia. By targeting IL-5 and disrupting its signaling pathway, reslizumab aims to inhibit the maturation of eosinophils and promote programmed cell death. Reslizumab is sold as Cinqaero in Europe.

SDS-PAGE for Reslizumab Biosimilar - Anti-IL5 mAb - Research Grade

SDS-PAGE for Reslizumab Biosimilar - Anti-IL5 mAb - Research Grade

Reslizumab Biosimilar - Anti-IL5 mAb - Research Grade, on SDS-PAGE. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.

SEC-HPLC of Reslizumab Biosimilar - Anti-IL5 mAb - Research Grade

SEC-HPLC of Reslizumab Biosimilar - Anti-IL5 mAb - Research Grade

Reslizumab Biosimilar - Anti-IL5 mAb - Research Gradewas analyzed by size exclusion chromatography with UV detection.

Reslizumab Biosimilar - Anti-IL5 mAb - Research Grade

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