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Brand: ProteoGenix

Margetuximab Biosimilar – Anti-ERBB2, EGFR2, CD340 mAb – Research Grade

Isotype:
IgG1, kappa

€120.00

+ 120 loyalty points
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Margetuximab Biosimilar - Anti-ERBB2, EGFR2, CD340 mAb - Research Grade

Margetuximab Biosimilar - Anti-ERBB2, EGFR2, CD340 mAb - Research Grade

Product name Margetuximab Biosimilar - Anti-ERBB2, EGFR2, CD340 mAb - Research Grade
Source CAS 1350624-75-7
Species Chimeric
Purity >85%
Buffer PBS buffer PH7.5
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition store at -80°C
Brand ProteoGenix
Applications ELISA,WB
Aliases /Synonyms Margetuximab,MGAH-22,ERBB2, EGFR2, CD340,anti-ERBB2, EGFR2, CD340
Reference PX-TA1331
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG1-kappa
Clonality Monoclonal Antibody
Product name Margetuximab Biosimilar - Anti-ERBB2, EGFR2, CD340 mAb - Research Grade
Source CAS 1350624-75-7
Species Chimeric
Expression system Mammalian cells
Purity >85%
Buffer PBS buffer PH7.5
Delivery condition Blue ice (+4°C)
Delivery Time 3-5 days if in stock; 3-5 weeks if production needed
Storage condition store at -80°C
Brand ProteoGenix
Applications ELISA,WB,,,
Aliases /Synonyms Margetuximab,MGAH-22,ERBB2, EGFR2, CD340,anti-ERBB2, EGFR2, CD340
Reference PX-TA1331
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype IgG1-kappa
Clonality Monoclonal Antibody

General information on Anti-ERBB2/EGFR2/CD340[Homo sapiens] (Margetuximab) Monoclonal Antibody

Margetuximab is an Fc-engineered human/mouse chimeric anti-HER2 monoclonal antibody of isotype IgG1 kappa . Margetuximab targets the same epitope on the HER2 extracellular domain and hass the same activity as trastuzumab. However, margetuximab has a higher affinity for both CD16A variants and a weaker one to the inhibitory CD32B Fc receptor, thereby resulting in more efficient antibody-dependent cell-mediated cytotoxicity (ADCC) and higher efficacy compared to trastuzumab. Margetuximab has been marketed under the trade name Margenza.

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