Interleukin-18(IL18)

Reference:
Size

10ug, 100ug

Brand

Product type

Host Species

Description of Interleukin-18(IL18)

Description of Interleukin-18(IL18)

General Information about Interleukin-18 (IL18)

IL-18 belongs to the IL-1 superfamily and is mainly produced by macrophages, but also produced by other cell types, stimulating various cell types and having pleiotropic functions. IL-18 is a pro-inflammatory cytokine that pro-inflammatory type 1 response. Together with IL-12, it induces cell-mediated immunity after infection with microbial products such as lipopolysaccharide (LPS). IL-18 and IL12 combine to act on CD4, CD8 T cells and NK cells to induce the production of IFN?. Type II interferon plays an important role in activating macrophages or other cells. It has been demonstrated that this combination of IL-18 and IL-12 inhibits the production of IL-4-dependent IgE and IgG1 in B cells and enhances the production of IgG2a. Importantly, without IL-12 or IL-15, IL-18 does not induce the production of IFN?, but plays an important role in the differentiation of naive T cells into Th2 cells and stimulates mast cells and basophils to produce IL-4, IL-13, and chemical mediators such as histamine.

Product nameInterleukin-18(IL18)
Expression systemProcaryotic expression
Molecular weight19.45kDa
Purity estimated>95% by SDS-PAGE
BufferPBS pH 7.5
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesEscherichia coli (E.coli)
Fragment TypeTyr37-Asp193
Aliases /SynonymsIGIF, IL1F4,Iboctadekin,Interferon gamma-inducing factor2 Publications,IFN-gamma-inducing factor2 Publications,Interleukin-1 gamma,IL-1 gamma
ReferencePX-P4562
NoteFor research use only
Product nameInterleukin-18(IL18)
Expression systemProcaryotic expression
Molecular weight19.45kDa
Purity estimated>95% by SDS-PAGE
BufferPBS pH 7.5
Delivery conditionDry Ice
Storage condition4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
BrandProteoGenix
Host speciesEscherichia coli (E.coli)
Fragment TypeTyr37-Asp193
Aliases /SynonymsIGIF, IL1F4,Iboctadekin,Interferon gamma-inducing factor2 Publications,IFN-gamma-inducing factor2 Publications,Interleukin-1 gamma,IL-1 gamma
ReferencePX-P4562
NoteFor research use only

Reviews

There are no reviews yet.

Be the first to review “Interleukin-18(IL18)”

Your email address will not be published.

Clear
OK

Please select the country of delivery so that we can send you the quotation including shipping costs.

Thank you for your request! You will receive your quotation per e-mail in a few seconds.

If you did not receive your quotation, please check your spam folder.

Contact us to order

+33 (0)3 90 20 54 70

Write us

Categories: