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Brand: ProteoGenix

Human NECTIN4-PVRL4 recombinant protein

Host species:
Mammalian cells
Origin species:
Homo sapiens (Human)
Uniprot ID:
Q96NY8
Molecular weight:
38.41 kDa

420.00

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Met1–Ser349 His
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Human NECTIN4-PVRL4 recombinant protein

Product name Human NECTIN4-PVRL4 recombinant protein
Uniprot ID Q96NY8
Origin species Homo sapiens (Human)
Expression system Eukaryotic expression
Molecular weight 38.41 kDa
Protein delivered with Tag? C-Terminal His Tag
Purity estimated >85% by SDS-PAGE
Buffer 0.01M PBS, pH 7.4.
Delivery condition Dry Ice
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Mammalian cells
Fragment Type Met1-Ser349
Aliases /Synonyms LNIR, NECTIN4, PRR4, Poliovirus receptor-related protein 4, Nectin cell adhesion molecule 4, Ig superfamily receptor LNIR, Nectin-4, PVRL4, Drug Target
Reference PX-P6108
Note For research use only.
Molecular Constructor
Met1–Ser349 His

General information on Human NECTIN4-PVRL4 recombinant protein

Structure

Human NECTIN4-PVRL4 recombinant protein is a type I transmembrane glycoprotein composed of two extracellular immunoglobulin-like domains, a single transmembrane domain, and a short cytoplasmic tail. It is expressed on the cell surface of various epithelial cells.

Activity

The NECTIN4-PVRL4 protein is involved in cell-cell adhesion, cell-matrix adhesion, and cell-signaling processes. It is also involved in the regulation of cell proliferation, migration, and differentiation.

Application

Human NECTIN4-PVRL4 recombinant protein is used in research to study the role of NECTIN4-PVRL4 in diseases such as cancer, inflammation, and immune-related disorders. It is also used as an antibody-drug target for the development of novel therapeutics.

Enfortumab Biosimilar – Anti-PVRL4 mAb – Research Grade binds to Human NECTIN4-PVRL4 recombinant protein in indirect ELISA Assay

Enfortumab Biosimilar – Anti-PVRL4 mAb – Research Grade binds to Human NECTIN4-PVRL4 recombinant protein in indirect ELISA Assay

Immobilized Human NECTIN4-PVRL4 recombinant protein (cat. No.PX-P6108) at 0.5µg/mL (100µL/well) can bind to Enfortumab Biosimilar- Anti-PVRL4 mAb- Research Grade (cat. No.PX-TA1333) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450

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