Recombinant Human CC2D1A, N-His

Introduction

Recombinant Human CC2D1A is a protein that has been genetically engineered in a laboratory setting to mimic the function of the naturally occurring CC2D1A protein. This recombinant protein has been extensively studied and has shown promising potential in various scientific applications. In this article, we will explore the structure, activity, and potential applications of Recombinant Human CC2D1A.

Structure of Recombinant Human CC2D1A

The CC2D1A protein is a member of the coiled-coil and C2 domain-containing protein family. It is composed of 1,403 amino acids and has a molecular weight of approximately 160 kDa. The recombinant version of this protein is produced by inserting the gene encoding CC2D1A into a suitable expression vector and then expressing it in a host organism, typically a bacterial or mammalian cell line.

The recombinant protein is then purified using various techniques such as affinity chromatography and size exclusion chromatography to obtain a highly pure and functional protein. Recombinant Human CC2D1A has been shown to have a similar structure to the naturally occurring protein, with a coiled-coil domain at the N-terminus and a C2 domain at the C-terminus.

Activity of Recombinant Human CC2D1A

The CC2D1A protein is involved in various cellular processes, including gene regulation, cell signaling, and protein-protein interactions. The recombinant version of this protein has been shown to exhibit similar activities to the native protein, making it a valuable tool for studying the function of CC2D1A in various biological systems.

One of the key activities of CC2D1A is its role in regulating the Wnt signaling pathway. This pathway is involved in various cellular processes, including cell proliferation, differentiation, and survival. Recombinant Human CC2D1A has been shown to interact with key components of the Wnt pathway, such as Dishevelled and Axin, and modulate their activity.

In addition to its role in Wnt signaling, CC2D1A has also been implicated in the regulation of gene expression. It has been shown to interact with transcription factors and chromatin remodeling proteins, suggesting a role in gene transcription and epigenetic regulation.

Applications of Recombinant Human CC2D1A

Recombinant Human CC2D1A has a wide range of potential applications in the field of biomedical research. Its ability to mimic the function of the native protein makes it a valuable tool for studying the role of CC2D1A in various cellular processes.

One potential application of this protein is in the development of therapeutics targeting the Wnt signaling pathway. As CC2D1A has been shown to interact with key components of this pathway, it could potentially be targeted to modulate Wnt signaling in diseases such as cancer and neurodegenerative disorders.

Recombinant Human CC2D1A could also be used in drug discovery and development. By studying its interactions with other proteins and its role in gene regulation, researchers could identify potential drug targets and develop new therapies for various diseases.

Furthermore, this protein could also be used in diagnostic applications. As CC2D1A has been linked to various diseases, including autism and intellectual disability, it could potentially serve as a biomarker for these conditions.

Conclusion

Recombinant Human CC2D1A is a valuable tool in the field of biomedical research. Its similar structure and activity to the native protein make it a powerful tool for studying the function of CC2D1A in various cellular processes. With its potential applications in drug discovery, therapeutics, and diagnostics, this protein holds great promise for the future of scientific research.