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ProteoGenix
Recombinant Proteins
Escherichia coli (E. coli)
Elisa, WB
MSP1-p19 (Merozoite surface proteins) is a protein located on the surface of Plasmodium falciparum merozoites. The protein is a good target for vaccine development against malaria, a disease caused by protozoans because they are accessible to antibodies in the plasma. It also induce both inhibitory as well as blocking antibodies, the latter blocking the protective effects of the former. The malaria parasite, in its asexual, blood invading stage called the merozoite stage, infects red blood cells. The MSP1 complex of surface proteins likely mediates the first interactions of the parasite with red blood cells.
Publication
1: Hellgren O, Kutzer M, Bensch S, Valkiūnas G, Palinauskas V. Identification and characterization of the merozoite surface protein 1 (msp1) gene in a host-generalist avian malaria parasite, Plasmodium relictum (lineages SGS1 and GRW4) with the use of blood transcriptome. Malar J. 2013 Oct 30;12:381. doi: 10.1186/1475-2875-12-381. PubMed PMID: 24172200; PubMed Central PMCID: PMC3827925.
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