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Brand: ProteoGenix

Monkeypox virus/MPXV M1R Monoclonal Antibody SAA0284

260.00

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Monkeypox virus/MPXV M1R Monoclonal Antibody SAA0284

Product name Monkeypox virus/MPXV M1R Monoclonal Antibody SAA0284
Form Liquid in PBS buffer, pH 7.4
Delivery condition Blue ice (+4°C)
Delivery lead time in business days 3-5 days if in stock; 3-5 weeks if production needed
Storage condition 4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Brand ProteoGenix
Host species Mouse
Reactivity Monkeypox virus(MPXV)
Reference PTX18822
Isotype IgG2a, kappa
Clonality Monoclonal Antibody
Immunogen M1R
Clone Name SAA0284
Protein Name M1R
Target species Anti-Monkeypox virus(MPXV) Monoclonal Antibody

Structure of Monkeypox Virus M1R Monoclonal Antibody

Monkeypox virus M1R monoclonal antibody is a type of IgG1 antibody, which is composed of two heavy chains and two light chains. Each chain contains a variable region that is specific for the target antigen, and a constant region that is responsible for binding to the B-cell receptor and other molecules involved in the immune response.

Activity of Monkeypox Virus M1R Monoclonal Antibody

The M1R monoclonal antibody binds to the surface of the monkeypox virus, preventing it from entering the cells of the host organism. This prevents the virus from replicating and spreading, thus providing protection against infection.

Application of Monkeypox Virus M1R Monoclonal Antibody

The M1R monoclonal antibody can be used for research purpose only in monkeypox virus infections.

Detects Monkeypox virus/MPXV M1R in direct ELISAs.

Detects Monkeypox virus/MPXV M1R in direct ELISAs.

Immobilized Recombinant Monkeypox virus/MPXV M1R Protein (cat. No.PX-P6056) at 0.5µg/mL (100µL/well) can bind Monkeypox virus/MPXV M1R Monoclonal Antibody SAA0284 (cat. No.PTX18822) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450 giving an EC50 at 85.41M.

SDS-PAGE For Monkeypox virus/MPXV M1R Monoclonal Antibody SAA0284

SDS-PAGE For Monkeypox virus/MPXV M1R Monoclonal Antibody SAA0284

Monkeypox virus/MPXV M1R Monoclonal Antibody SAA0284, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

  • Zuiani et al., A multivalent mRNA monkeypox virus vaccine (BNT166) protects mice and macaques from orthopoxvirus disease, 2024, Cell 187, 1–11March 14, 2024 https://doi.org/10.1016/j.cell.2024.01.017
  • Pandiaraj Kanagavalli, Ragi Adham Elkaffas, Shimaa Eissa, Ultrasensitive electrochemical biosensor for the simultaneous detection of the two monkeypox virus antigens M1R and A29 using reduced graphene oxide-ZIF-8 nanocomposite, Chemical Engineering Journal, Volume 516, 2025, 164015, ISSN 1385-8947, https://doi.org/10.1016/j.cej.2025.164015

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