4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand
ProteoGenix
Host species
Mammalian cells
Fragment Type
Met1-Ser349
Aliases /Synonyms
LNIR, NECTIN4, PRR4, Poliovirus receptor-related protein 4, Nectin cell adhesion molecule 4, Ig superfamily receptor LNIR, Nectin-4, PVRL4, Drug Target
Reference
PX-P6108
Note
For research use only
Description of Human NECTIN4-PVRL4 recombinant protein
General information on Human NECTIN4-PVRL4 recombinant protein
Structure
Human NECTIN4-PVRL4 recombinant protein is a type I transmembrane glycoprotein composed of two extracellular immunoglobulin-like domains, a single transmembrane domain, and a short cytoplasmic tail. It is expressed on the cell surface of various epithelial cells.
Activity
The NECTIN4-PVRL4 protein is involved in cell-cell adhesion, cell-matrix adhesion, and cell-signaling processes. It is also involved in the regulation of cell proliferation, migration, and differentiation.
Application
Human NECTIN4-PVRL4 recombinant protein is used in research to study the role of NECTIN4-PVRL4 in diseases such as cancer, inflammation, and immune-related disorders. It is also used as an antibody-drug target for the development of novel therapeutics.
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