The Anti-VCAN Polyclonal Antibody is a highly specific and sensitive tool for detecting and quantifying VCAN (Versican) protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a unique sequence in the VCAN protein.
Biological Function:
VCAN, also known as chondroitin sulfate proteoglycan 2 or versican core protein, is a large extracellular matrix (ECM) protein that plays a crucial role in cell adhesion, migration, and proliferation. It is involved in various physiological processes, including tissue development, wound healing, and inflammation. VCAN is also implicated in several pathological conditions, such as cancer, cardiovascular diseases, and neurological disorders.
Main Applications:
The Anti-VCAN Polyclonal Antibody is suitable for a wide range of applications, including Western blotting, immunofluorescence, immunohistochemistry, and ELISA. It can be used to detect VCAN protein in different sample types, including tissue lysates, cell culture supernatants, and body fluids. This antibody has been validated for use in human, mouse, and rat samples.
Experimental Use Cases:
1. Cancer Research: VCAN is overexpressed in various types of cancer, and its expression is associated with tumor growth, invasion, and metastasis. The Anti-VCAN Polyclonal Antibody can be used to study the role of VCAN in cancer progression and to identify potential therapeutic targets.
2. Cardiovascular Disease: VCAN has been implicated in the development of atherosclerosis and other cardiovascular diseases. The Anti-VCAN Polyclonal Antibody can be used to investigate the involvement of VCAN in these conditions and to assess its potential as a biomarker for disease diagnosis and prognosis.
3. Neurological Disorders: VCAN is involved in the formation and maintenance of the central nervous system (CNS) and has been linked to various neurological disorders, such as Alzheimer’s disease and multiple sclerosis. The Anti-VCAN Polyclonal Antibody can be used to study the role of VCAN in CNS development and disease progression.
In summary, the Anti-VCAN Polyclonal Antibody is a highly specific and versatile tool for studying the function and expression of VCAN in various biological samples. With its reliable performance and broad applications, this antibody is an essential tool for researchers in the fields of cancer, cardiovascular disease, and neuroscience. Order now and accelerate your research with confidence.
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