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Brand: ProteoGenix

Anti-Mouse MMP3 Antibody (CH01)

  • ARO-A15080-100
  • Validated ELISA FC

Original price was: €417.00.Current price is: €342.00.

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Anti-Mouse MMP3 Antibody (CH01)

Product name ARO-A15080-100
Uniprot ID P28862
Raw Antigen Sequence MKGLPVLLWLCVVVCSSYPLHDSARDDDAGMELLQKYLENYYGLAKDVKQFIKKKDSSLIVKKIQEMQKFLGLEMTGKLDSNTMELMHKPRCGVPDVGGFSTFPGSPKWRKSHITYRIVNYTPDLPRQSVDSAIEKALKVWEEVTPLTFSRISEGEADIMISFAVGEHGDFVPFDGPGTVLAHAYAPGPGINGDAHFDDDERWTEDVTGTNLFLVAAHELGHSLGLYHSAKAEALMYPVYKSSTDLSRFHLSQDDVDGIQSLYGTPTASPDVLVVPTKSNSLEPETSPMCSSTLFFDAVSTLRGEVLFFKDRHFWRKSLRTPEPEFYLISSFWPSLPSNMDAAYEVTNRDTVFIFKGNQFWAIRGHEELAGYPKSIHTLGLPATVKKIDAAISNKEKRKTYFFVEDKYWRFDEKKQSMEPGFPRKIAEDFPGVDSRVDAVFEAFGFLYFFSGSSQLEFDPNAKKVTHILKSNSWFNC
Form 0.01M PBS, pH 7.4.
Delivery condition Blue ice (+4°C)
Storage condition 4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Brand ProteoGenix
Host species Rat
Reactivity Human, Mouse, Rat
Reference ARO-A15080
Isotype IgG1, kappa
Clonality Monoclonal Antibody
Purification Protein A or G purified from cell culture supernatant.
Immunogen SL-1, Transin-1, MMP-3, MMP3, Matrix metalloproteinase-3, Stromelysin-1, STMY1
Target species Anti-Human, Mouse, Rat Monoclonal Antibody
Product name ARO-A15080-1MG
Uniprot ID P28862
Raw Antigen Sequence MKGLPVLLWLCVVVCSSYPLHDSARDDDAGMELLQKYLENYYGLAKDVKQFIKKKDSSLIVKKIQEMQKFLGLEMTGKLDSNTMELMHKPRCGVPDVGGFSTFPGSPKWRKSHITYRIVNYTPDLPRQSVDSAIEKALKVWEEVTPLTFSRISEGEADIMISFAVGEHGDFVPFDGPGTVLAHAYAPGPGINGDAHFDDDERWTEDVTGTNLFLVAAHELGHSLGLYHSAKAEALMYPVYKSSTDLSRFHLSQDDVDGIQSLYGTPTASPDVLVVPTKSNSLEPETSPMCSSTLFFDAVSTLRGEVLFFKDRHFWRKSLRTPEPEFYLISSFWPSLPSNMDAAYEVTNRDTVFIFKGNQFWAIRGHEELAGYPKSIHTLGLPATVKKIDAAISNKEKRKTYFFVEDKYWRFDEKKQSMEPGFPRKIAEDFPGVDSRVDAVFEAFGFLYFFSGSSQLEFDPNAKKVTHILKSNSWFNC
Form 0.01M PBS, pH 7.4.
Delivery condition Blue ice (+4°C)
Storage condition 4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Brand ProteoGenix
Host species Rat
Reactivity Human, Mouse, Rat
Reference ARO-A15080
Isotype IgG1, kappa
Clonality Monoclonal Antibody
Purification Protein A or G purified from cell culture supernatant.
Immunogen SL-1, Transin-1, MMP-3, MMP3, Matrix metalloproteinase-3, Stromelysin-1, STMY1
Target species Anti-Human, Mouse, Rat Monoclonal Antibody
Product name ARO-A15080-50
Uniprot ID P28862
Raw Antigen Sequence MKGLPVLLWLCVVVCSSYPLHDSARDDDAGMELLQKYLENYYGLAKDVKQFIKKKDSSLIVKKIQEMQKFLGLEMTGKLDSNTMELMHKPRCGVPDVGGFSTFPGSPKWRKSHITYRIVNYTPDLPRQSVDSAIEKALKVWEEVTPLTFSRISEGEADIMISFAVGEHGDFVPFDGPGTVLAHAYAPGPGINGDAHFDDDERWTEDVTGTNLFLVAAHELGHSLGLYHSAKAEALMYPVYKSSTDLSRFHLSQDDVDGIQSLYGTPTASPDVLVVPTKSNSLEPETSPMCSSTLFFDAVSTLRGEVLFFKDRHFWRKSLRTPEPEFYLISSFWPSLPSNMDAAYEVTNRDTVFIFKGNQFWAIRGHEELAGYPKSIHTLGLPATVKKIDAAISNKEKRKTYFFVEDKYWRFDEKKQSMEPGFPRKIAEDFPGVDSRVDAVFEAFGFLYFFSGSSQLEFDPNAKKVTHILKSNSWFNC
Form 0.01M PBS, pH 7.4.
Delivery condition Blue ice (+4°C)
Storage condition 4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Brand ProteoGenix
Host species Rat
Reactivity Human, Mouse, Rat
Reference ARO-A15080
Isotype IgG1, kappa
Clonality Monoclonal Antibody
Purification Protein A or G purified from cell culture supernatant.
Immunogen SL-1, Transin-1, MMP-3, MMP3, Matrix metalloproteinase-3, Stromelysin-1, STMY1
Target species Anti-Human, Mouse, Rat Monoclonal Antibody

Introduction

Anti-Mouse MMP3 Antibody (CH01) is a highly specific and potent monoclonal antibody that targets the matrix metalloproteinase 3 (MMP3) protein in mice. MMP3 is a member of the matrix metalloproteinase family, which are enzymes involved in the breakdown of extracellular matrix proteins. MMP3 has been implicated in various physiological and pathological processes, making it a promising therapeutic target for a range of diseases. In this article, we will provide a detailed description of the structure, activity, and potential applications of Anti-Mouse MMP3 Antibody (CH01).

Structure of Anti-Mouse MMP3 Antibody (CH01)

Anti-Mouse MMP3 Antibody (CH01) is a monoclonal antibody, meaning it is derived from a single clone of immune cells. It is produced by hybridoma cells, which are created by fusing a specific type of immune cell with a cancer cell. This fusion results in a hybrid cell that has the ability to continuously produce large quantities of the desired antibody. The antibody has a molecular weight of approximately 150 kDa and is composed of two heavy chains and two light chains. The heavy chains are further divided into constant and variable regions, with the variable regions being responsible for binding to the target protein, MMP3.

Activity of Anti-Mouse MMP3 Antibody (CH01)

The main function of Anti-Mouse MMP3 Antibody (CH01) is to specifically bind to MMP3 and inhibit its activity. This is achieved through the binding of the antibody’s variable regions to specific regions on the MMP3 protein, preventing it from carrying out its enzymatic function. MMP3 is known to play a crucial role in various physiological processes, such as tissue remodeling, wound healing, and angiogenesis. However, dysregulation of MMP3 has been linked to various diseases, including cancer, arthritis, and cardiovascular diseases. By inhibiting the activity of MMP3, Anti-Mouse MMP3 Antibody (CH01) has the potential to modulate these disease processes and provide therapeutic benefits.

Applications of Anti-Mouse MMP3 Antibody (CH01)

Anti-Mouse MMP3 Antibody (CH01) has a wide range of potential applications in both research and therapeutic settings. In research, the antibody can be used as a tool to study the role of MMP3 in various disease processes. It can also be used in experiments to validate the efficacy of potential MMP3 inhibitors. In addition, Anti-Mouse MMP3 Antibody (CH01) can be used in diagnostic assays to measure the levels of MMP3 in biological samples, providing valuable information about disease progression and response to treatment.
In terms of therapeutic applications, Anti-Mouse MMP3 Antibody (CH01) has the potential to be used as a targeted therapy for diseases where MMP3 is dysregulated. For example, in cancer, MMP3 has been shown to promote tumor growth and metastasis. By inhibiting MMP3 activity, Anti-Mouse MMP3 Antibody (CH01) could potentially slow down tumor growth and prevent metastasis. In addition, MMP3 has been implicated in the progression of arthritis by promoting cartilage degradation. Anti-Mouse MMP3 Antibody (CH01) could potentially be used to slow down the progression of arthritis and alleviate symptoms.

Conclusion

In summary, Anti-Mouse MMP3 Antibody (CH01) is a highly specific and potent monoclonal antibody that targets the MMP3 protein in mice. Its structure, activity, and potential applications make it a valuable tool for both research and therapeutic purposes. With further studies and development, Anti-Mouse MMP3 Antibody (CH01) has the potential to be a promising therapeutic agent for diseases where MMP3 is dysregulated, providing new treatment options for patients.

Flow Cytometry results for Anti-Mouse MMP3 Antibody (CH01)

Flow Cytometry results for Anti-Mouse MMP3 Antibody (CH01)

Target Cells were stained with an irrelevant antibody or Anti-Mouse MMP3 Antibody (CH01) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG Polyclonal Antibody, FITC (PTX18862) and cells analysed on a NovoCyte Flow Cytometer.

Anti-Mouse MMP3 Antibody (CH01) binds to Recombinant Mouse MMP3 Protein, N-His in ELISA Assay

Anti-Mouse MMP3 Antibody (CH01) binds to Recombinant Mouse MMP3 Protein, N-His in ELISA Assay

Recombinant Mouse MMP3 Protein, N-His(cat. No.ARO-P10590) at 0.5µg/mL (100µL/well) can bind Anti-Mouse MMP3 Antibody (CH01) in indirect ELISA with Goat secondary antibody measured by OD450.

Anti-Mouse MMP3 Antibody (CH01)

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