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View ProductsSize | 100ug, 1MG |
---|---|
Brand | ProteoGenix |
Isotype | IgG4, kappa |
Product type | Primary Antibodies |
Clonality | Monoclonal Antibody |
Expression system | XtenCHO |
Product name | Vixticibart Biosimilar - Anti-ANP-A mAb - Research Grade |
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Source | CAS: 2845128-05-2 |
Origin species | Human |
Expression system | XtenCHO |
Purity | >95% by SDS-PAGE |
Buffer | 0.01M PBS, pH 7.4 |
Delivery condition | Blue ice (+4°C) |
Delivery lead time in business days | 3-5 days if in stock; 3-5 weeks if production needed |
Storage condition | 4°C for short term; -20°C for long term |
Brand | ProteoGenix |
Aliases /Synonyms | anti-ANP-A, Atrial natriuretic peptide receptor type A, Guanylate cyclase A, NPR1, NPR-A, ANPRA, GC-A, ANPR-A, Atrial natriuretic peptide receptor 1 |
Reference | PX-TA2194-100 |
Note | For research use only. Not suitable for human use. |
Isotype | IgG4-kappa |
Clonality | Monoclonal Antibody |
Vixticibart Biosimilar is a novel therapeutic antibody targeting the anti-atrial natriuretic peptide-A (ANP-A) protein. This biosimilar is a research grade product that has been designed to mimic the structure and function of the original therapeutic antibody, providing a valuable tool for scientists and researchers in the field of cardiovascular diseases. In this article, we will discuss the structure, activity and potential applications of Vixticibart Biosimilar in detail.
Vixticibart Biosimilar is a monoclonal antibody, meaning it is produced from a single clone of cells and has a highly specific binding affinity for its target protein, ANP-A. The antibody is composed of two identical heavy chains and two identical light chains, connected by disulfide bonds. The heavy chains contain a constant region and a variable region, while the light chains only have a variable region. The variable regions of both the heavy and light chains are responsible for binding to the target protein.
The amino acid sequence of Vixticibart Biosimilar has been carefully engineered to closely resemble the original therapeutic antibody, ensuring its specificity and effectiveness. This biosimilar also contains a human IgG1 constant region, making it less likely to cause an immune reaction in patients.
The primary activity of Vixticibart Biosimilar is its ability to bind to ANP-A, a hormone produced by the heart that plays a critical role in regulating blood pressure and fluid balance. By binding to ANP-A, Vixticibart Biosimilar can prevent its interaction with its receptor, thereby blocking its activity. This can have a beneficial effect on patients with cardiovascular diseases, as excessive levels of ANP-A have been linked to conditions such as hypertension and heart failure.
In addition to its binding activity, Vixticibart Biosimilar also has an effector function, meaning it can activate the immune system to destroy cells that have been bound by the antibody. This can be useful in cases where the target protein is expressed on the surface of diseased cells, such as cancer cells.
Vixticibart Biosimilar has a wide range of potential applications in both research and clinical settings. In research, this biosimilar can be used as a tool to study the role of ANP-A in various diseases, as well as to investigate the efficacy of different therapeutic interventions targeting this protein. It can also be used in preclinical studies to evaluate the safety and effectiveness of potential ANP-A targeting drugs.
In a clinical setting, Vixticibart Biosimilar has the potential to be used as a treatment for cardiovascular diseases, particularly those related to ANP-A dysregulation. By blocking the activity of ANP-A, this biosimilar may be able to reduce blood pressure and improve fluid balance in patients with hypertension or heart failure. It may also have potential as a treatment for other conditions where ANP-A has been implicated, such as pulmonary hypertension and kidney diseases.
In summary, Vixticibart Biosimilar is a research grade therapeutic antibody targeting ANP-A, a hormone involved in regulating blood pressure and fluid balance. Its carefully engineered structure and specific binding activity make it a valuable tool for scientists and researchers studying cardiovascular diseases. It also has potential as a treatment for these diseases in clinical settings. Further research and clinical trials will be needed to fully understand the potential of Vixticibart Biosimilar and its role in improving patient outcomes.
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