Recombinant Human TRPC4AP Protein, N-His

Description of Recombinant Human TRPC4AP Protein, N-His

Introduction

Recombinant Human TRPC4AP Protein is a highly specialized protein that plays a crucial role in various cellular processes. This protein is produced through recombinant DNA technology, making it a valuable tool for research and therapeutic applications.

Structure of Recombinant Human TRPC4AP Protein

The Recombinant Human TRPC4AP Protein is a 55 kDa protein consisting of 507 amino acids. It belongs to the TRP (Transient Receptor Potential) superfamily of ion channels and is specifically classified as a TRP cation channel subfamily C member 4-associated protein (TRPC4AP). The protein is composed of several domains, including a coiled-coil domain, a TRP domain, and a C-terminal PDZ-binding motif. These domains are essential for the protein’s function and interaction with other molecules.

Activity of Recombinant Human TRPC4AP Protein

The main function of Recombinant Human TRPC4AP Protein is to regulate the activity of TRPC4 channels. These channels are non-selective cation channels that play a crucial role in calcium signaling and cell growth. TRPC4AP acts as a scaffold protein, binding to the C-terminus of TRPC4 channels and regulating their activity. This regulation is achieved through the coiled-coil domain, which interacts with other proteins to form a complex that modulates the opening and closing of TRPC4 channels.

In addition to its role in regulating TRPC4 channels, Recombinant Human TRPC4AP Protein also plays a role in cellular signaling pathways. It has been shown to interact with other proteins involved in cellular processes such as cell migration, apoptosis, and cell cycle regulation. This makes it a potential target for therapeutic interventions in diseases related to these processes.

Application of Recombinant Human TRPC4AP Protein

The use of Recombinant Human TRPC4AP Protein has been instrumental in advancing research in the field of calcium signaling and cellular processes. Its ability to regulate TRPC4 channels and interact with other proteins has made it a valuable tool for studying the role of these channels in various physiological and pathological conditions.

One of the main applications of Recombinant Human TRPC4AP Protein is in drug discovery and development. As TRPC4 channels have been implicated in various diseases, targeting these channels with specific inhibitors or activators could lead to the development of novel therapeutics. Recombinant Human TRPC4AP Protein can be used to screen potential compounds for their ability to modulate TRPC4 channel activity, providing valuable insights for drug development.

Another potential application of Recombinant Human TRPC4AP Protein is in cancer research. Studies have shown that TRPC4 channels play a role in the proliferation and migration of cancer cells. As TRPC4AP regulates the activity of these channels, it could be a potential target for cancer therapy. Recombinant Human TRPC4AP Protein can be used to study the interaction between TRPC4AP and TRPC4 channels in cancer cells, providing a better understanding of the underlying mechanisms and potential therapeutic interventions.

Conclusion

In summary, Recombinant Human TRPC4AP Protein is a versatile protein with a crucial role in regulating TRPC4 channels and cellular signaling pathways. Its structure, activity, and potential applications make it a valuable tool for research and therapeutic purposes. As our understanding of its function and interaction with other proteins continues to grow, Recombinant Human TRPC4AP Protein could hold even more potential for future advancements in the field of biology and medicine.