Brand: ProteoGenix

Human PD-L2 recombinant protein

PX-P6014-100
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Host species:: Mammalian cells
Origin species:: Homo sapiens (Human)
Uniprot ID:: Q9BQ51
Molecular weight:: 23.62 kDa

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Met1–Thr220 His

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Human PD-L2 recombinant protein

Product name	Human PD-L2 recombinant protein
Uniprot ID	Q9BQ51
Uniprot link	https://www.uniprot.org/uniprot/Q9BQ51
Origin species	Homo sapiens (Human)
Expression system	Eukaryotic expression
Molecular weight	23.62 kDa
Protein delivered with Tag?	C-terminal His Tag
Purity estimated	>85% by SDS-PAGE
Buffer	PBS, pH7.5
Delivery condition	Dry Ice
Storage condition	4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand	ProteoGenix
Host species	Mammalian cells
Fragment Type	Met1-Thr220
Aliases /Synonyms	PDCD1 ligand 2, B7-DC, PD-L2, PDCD1LG2, PDCD1L2, PDL2, Butyrophilin B7-DC, Programmed death ligand 2, Programmed cell death 1 ligand 2, CD273, B7DC, PD-1 ligand 2
Reference	PX-P6014
Note	For research use only
Background information	Array
Molecular Constructor	Met1–Thr220 His

General information on Human PD-L2 recombinant protein

Structure

Human PD-L2 recombinant protein is a type I transmembrane glycoprotein and is a member of the B7 family of CD proteins. It consists of a single extracellular immunoglobulin-like domain, a transmembrane domain and a short cytoplasmic tail.

Activity

PD-L2 plays an important role in the regulation of immune responses by binding to its receptor PD-1 on the surface of T cells and B cells. This binding leads to the inhibition of the activation and proliferation of these cells, thus acting as an immune checkpoint protein.

Application

Human PD-L2 recombinant protein is used in antibody-drug target therapy, where it is used to develop antibodies that can bind to PD-L2 and block the PD-L2/PD-1 interaction. This can result in the activation and proliferation of T cells and B cells, thus enhancing the immune response against cancer cells.

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Human PD-L2 recombinant protein

Human PD-L2 recombinant protein

General information on Human PD-L2 recombinant protein

Structure

Activity

Application

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Human PD-L2 recombinant protein

Specifications Human PD-L2 recombinant protein

Description

General information on Human PD-L2 recombinant protein

Structure

Activity

Application

Documents

Reviews

Related products

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Human PD-L2 recombinant protein