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Galegenimab Biosimilar – Anti-HTRA mAb – Research Grade

Reference:
Size

100µg, 1MG

Isotype

Fab'-G1-kappa

Brand

ProteoGenix

Product type

Primary Antibodies

Clonality

Monoclonal Antibody

Expression system

XtenCHO

Applications

Elisa, WB

Product nameGalegenimab Biosimilar - Anti-HTRA mAb - Research Grade
SourceCAS: 2403683-24-7
SpeciesHumanized
Expression systemXtenCHO
BufferPBS buffer PH7.5
Delivery conditionBlue ice (+4°C)
Delivery lead time in business days3-5 days if in stock; 3-5 weeks if production needed
Delivery Time3-5 days if in stock; 3 week if production needed
Storage conditionstore at -80°C
BrandProteoGenix
Aliases /SynonymsGalegenimab,FHTR2163, RG-6147, RG6417, RO-7171009, RO7171009,HTRA,anti-HTRA
ReferencePX-TA1771
NoteFor research use only. Not suitable for clinical or therapeutic use.
ClonalityMonoclonal Antibody

Description of Galegenimab Biosimilar - Anti-HTRA mAb - Research Grade

Galegenimab Biosimilar – Anti-HTRA mAb – Research Grade

Galegenimab Biosimilar – Anti-HTRA mAb – Research Grade: A Revolutionary Antibody for Targeting HTRA Galegenimab Biosimilar, also known as Anti-HTRA mAb, is a highly promising therapeutic antibody that has been developed to target the human high temperature requirement A (HTRA) protein. This biosimilar is a research grade antibody that has shown great potential in treating various diseases and disorders associated with HTRA dysregulation. In this article, we will delve into the structure, activity, and potential applications of Galegenimab Biosimilar in the field of medicine.

Structure of Galegenimab Biosimilar

Galegenimab Biosimilar is a monoclonal antibody (mAb) that is specifically designed to target the HTRA protein. It is a recombinant antibody that is produced using advanced biotechnology techniques, making it highly specific and potent. The antibody is composed of two heavy chains and two light chains, which are linked together by disulfide bonds. The variable regions of the antibody are responsible for its high specificity towards HTRA, while the constant regions provide stability and effector functions.

Activity of Galegenimab Biosimilar

The primary function of Galegenimab Biosimilar is to bind to the HTRA protein and inhibit its activity. HTRA is a serine protease that is involved in various cellular processes, including protein folding, degradation, and stress response. However, dysregulation of HTRA has been linked to several diseases, such as cancer, neurodegenerative disorders, and cardiovascular diseases. By targeting and inhibiting HTRA, Galegenimab Biosimilar can potentially prevent or treat these diseases.

Moreover, Galegenimab Biosimilar also has effector functions that can enhance its therapeutic activity. It can activate the immune system to attack and destroy cancer cells, as well as induce cell death in diseased cells. This makes it a powerful weapon against diseases that are associated with HTRA dysregulation.

Potential Applications of Galegenimab Biosimilar

Galegenimab Biosimilar has a wide range of potential applications in the field of medicine. Its primary target, HTRA, has been implicated in various diseases, making this biosimilar a promising candidate for treating them. Some of the potential applications of Galegenimab Biosimilar are:

Cancer Treatment Several studies have shown that HTRA is overexpressed in various types of cancer, including breast, lung, and prostate cancer. This overexpression has been linked to tumor growth and metastasis. By inhibiting HTRA, Galegenimab Biosimilar can potentially slow down or even stop the progression of cancer, making it a valuable tool in cancer treatment.

Neurodegenerative Disorders

HTRA has also been implicated in neurodegenerative disorders, such as Alzheimer’s and Parkinson’s disease. Studies have shown that HTRA can contribute to the accumulation of misfolded proteins, which are a hallmark of these diseases. By targeting and inhibiting HTRA, Galegenimab Biosimilar can potentially prevent or slow down the progression of these disorders.

Cardiovascular Diseases

HTRA has been linked to cardiovascular diseases, such as atherosclerosis and heart failure. It has been shown to play a role in the development of plaques in the arteries and the progression of heart failure. By inhibiting HTRA, Galegenimab Biosimilar can potentially prevent or treat these diseases, improving the overall cardiovascular health of patients.

Conclusion

Galegenimab Biosimilar – Anti-HTRA mAb – Research Grade is

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